Synthesis and Approval Status of Epinephrine Hydrochloride
Epinephrine Hydrochloride was nominated for inclusion on the 503B Bulks List due to its broad therapeutic applicability across multiple medical conditions.
Dec 30，2025 API
Synthesis and Medical Application of 3-Amino-1-Hydroxyadamantane
In the field of chemical synthesis, 3-Amino-1-Hydroxyadamantane serves primarily as a key synthetic intermediate for the pharmaceutical molecule Vildagliptin.
Dec 30，2025 API
The Synthesis of Cinnamic Acid
Cinnamic acid can be synthesised with high yields and selectivities via Knoevenagel, Perkin, Pechman, Reformatsky, and Wittig reactions using various catalysts, alongside a range of waste reduction an
Dec 29，2025 API
Bis(2-ethylhexyl) Maleate: Toxicological Profile and Reaction Kinetics
Bis(2-ethylhexyl) maleate shows toxic metabolite accumulation and glutathione stress response; it undergoes Diels-Alder reaction with cyclopentadiene.
Dec 29，2025 API
5-Bromouracil: Mutagenic DNA Base Analogue
5-Bromouracil undergoes UV-induced deactivation via multiple excited-state pathways; its gracillin complex targets cancer cells selectively.
Dec 29，2025 Chemical Materials
3-Methylxanthine: Gut-Derived Metabolite
3-methylxanthine boosts cisplatin-induced ovarian cancer apoptosis via DRD1, and high-yield biosynthesis from theophylline/theobromine is achieved.
Dec 29，2025 Chemical Reagents
Vinyl Terminated Polydimethylsiloxane: Synthesis Strategies & Applications
Vinyl terminated polydimethylsiloxane is synthesized via alkoxysilane polycondensation/ring-opening copolymerization and used to prepare PTFE.
Dec 29，2025 API
Sodium 4-Phenylbutyrate in Urea Cycle Disorder Therapy
Sodium 4-phenylbutyrate (prodrug/HDAC inhibitor) treats urea cycle disorders, inhibits protein glycation, and suppresses experimental colitis.
Dec 29，2025 Drugs
Ginsenoside Re: Diverse Pharmacological Properties
Ginsenoside Re exerts anti-inflammatory/neuroprotective effects, undergoes deglycosylation/oxidation metabolism, and enhances health.
Dec 29，2025 API
8,10-Dodecadien-1-ol: Green Production and Its Core Applications
8,10-Dodecadien-1-ol works as a Grapholita molesta pheromone synergist and can be green-produced via transgenic plants for orchard pest control.
Dec 26，2025 Chemical Materials