Pyrroloquinoline quinone: Food sources, benefits and side effects

Pyrroloquinoline quinone (PQQ) is a quinone described as a cofactor for many bacterial dehydrogenases and reported to have effects on mammalian cell/tissue metabolism.

Mar 24,2025  API

FDA-approved drug Tofacitinib citrate: Brand name,Indications and Side Effects

Tofacitinib citrate is a Janus kinase (JAK) inhibitor, it treats adults with moderate to severe rheumatoid arthritis, active psoriatic arthritis, active ankylosing spondylitis, and moderate to severe

Mar 24,2025  API

Mirogabalin besylate:Indications, Advantages,Mechnaism of action and Side effects

Mirogabalin besylate is indicated for patients with peripheral neuropathic pain and central neuropathic pain after spinal cord injury and stroke, many of whom are elderly.

Mar 24,2025  API

Macitentan: a dual endothelin-receptor antagonist

Macitentan is an orally active, non-peptide, potent dual ERA and macitentan selectively inhibits the binding of endothelin-1 (ET-1) to ETA and ETB receptors.

Mar 24,2025  API

JAK inhibitor Upadacitinib:FDA approval,Brand name,Indications and Side effects

Upadacitinib received FDA approval on August 16, 2019, based on positive and promising results from its multinational phase III trials in subjects with moderate to severe rheumatoid arthritis.

Mar 24,2025  API

Betaine Hydrochloride: From Physiological Roles to Safety Evaluations

Betaine hydrochloride is endogenously synthesized through the metabolism of choline or exogenously consumed through dietary intake.

Mar 24,2025  Chemical Reagents

Selpercatinib (LOXO-292):Indications, Mechnaism,Clinical trials and Side effects

Selpercatinib (LOXO-292) is a highly selective RET inhibitor with activity across known oncogenic RET fusions and mutations.

Mar 21,2025  API

Fruquintinib:Indications,Trials and Side effects

Fruquintinib, as an oral tyrosine kinase inhibitor (TKI), effectively suppresses vascular endothelial growth factor/vascular endothelial growth factor receptor (VEGF/VEGFR) signaling and inhibits cell

Mar 21,2025  API

Structure, Thermostability and Multifarious Applications of Cellulases

Cellulases have been utilized in various commercial sectors including agriculture, brewing, laundry, pulp and paper and textile industry.

Mar 21,2025  Biochemical Engineering

3-Nitrophthalic Acid: A Key Compound in Organic Synthesis

3-Nitrophthalic acid can be used as starting reagent in the synthesis of modified 2-iodoxybenzoic acid derivatives.

Mar 21,2025  Chemical Reagents
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