Pd(OAc)2/Xantphos Catalyst System
A recent report by Eastgate and Blackmond on a Pd/Xantphos-catalyzed C?H arylation reaction suggested that under their reaction conditions, the active ligand was not Xantphos or Xantphos bisphosphine
Feb 22，2021 Organic Raw MaterialWhat is Lithium diisopropylamide?
Lithium diisopropylamide (commonly abbreviated LDA) is a chemical compound with the molecular formula [(CH3)2CH]2NLi. It is used as a strong base and has been widely utilized due to its good solubilit
Feb 22，2021 Organometallic compoundsWhat is Pectinase?
Pectinase is a collective term for enzymes that break down pectin and are as pectic enzymes. Polygalacturonase is one of the most well-known pectinase, and other common examples of this enzyme class i
Oct 28，2020 Food AdditivesEntratinib's mechanism of action
Entritinib was approved for marketing in Japan on June 19, 2019, and was approved by the FDA on August 15, 2019 for the treatment of advanced recurrent solid tumors with positive neurotrophic tyrosine
Oct 26，2020 API
Antimony - Medicinal Use Discovery and History
Red antimony trisulfide occurs naturally in stibnite, a mineral mentioned by Dioscorides and found in Hungary, France, Cornwall and Borneo.
Oct 23，2020 Inorganic chemistry
Arsphenamine - Drug Application, Reach Process and Discovery History
Antoine Be′champ synthesised the sodium salt of the meta-anilide of phenylarsonic acid in 1863. At the beginning of the twentieth century it was marketed by the Vereinigte Chemische Werke.
Oct 22，2020 Inorganic salts
Thyrotropin(TSH)-Chemistry, Action, Preparations and Stimulation Test
Thyroid stimulating hormone (TSH) is a glycoprotein of MW 28,000 that is synthesized by thyrotrope cells of the anterior pituitary.
Oct 21，2020 Hormones and the Endocrine System
Etacrynic acid - Drug Discovery, History, Mechanism of action etc.
In the 1950s, a novel approach to the problem of designing a non-toxic, potent diuretic was taken by a team of researchers from Sharp & Dohme, under the direction of Karl Beyer.
Oct 20，2020 Drugs
Your Skin Might Actually Need Ascorbyl Glucoside, Not Vitamin C
Case in point: Ascorbyl glucoside, which is a notably more stable, gentler take on the vitamin. Ahead, New York City dermatologist Marnie Nussbaum, MD, and Sheel Desai Solomon, MD, a dermatologist in
Oct 20，2020 Analytical Chemistry
Mercury - History and Drug-Application
Since around 500 BC, the mines at Sisapo in Almade′n (Arabic for the mine) in Southern Spain have been the principal source of Iberian cinnabar, red mercuric sulfide.
Oct 19，2020 Inorganic chemistry