| Identification | More | [Name]
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride | [CAS]
101152-94-7 | [Synonyms]
(1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
(1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIMETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
F 2207
IXEL
MIDALCIPRAN
MIDALCIPRAN HYDROCHLORIDE
MILNACIPRAN HCL
MILNACIPRAN HYDROCHLORIDE
TOLEDOMIN
1-phenyl-1-(diethylaminocarbonyl)-2-(aminomethyl)cyclopropanehydrochloride
2-(aminomethyl)-n,n-diethyl-1-phenyl-cyclopropanecarboxamidmonohydrochlori
cis-(+-)-2-(aminomethyl)-n,n-diethyl-1-phenylcyclopropanecarboxamidemonohydr
cis-(+-)-d
Milnacipran Hydrochloride (Subject to patent free)
(1R,2S)-rel-2(Amino-methyl)-N,N-diethyl-1-phenyl-cyclopropanecarboxamide, Monohydrochloride
Dalcipran
F 2207, Midalcipran, Toledomin, (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride
rel-2α*-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1α*-carboxamide·hydrochloride | [EINECS(EC#)]
620-477-4 | [Molecular Formula]
C15H23ClN2O | [MDL Number]
MFCD00901293 | [Molecular Weight]
282.81 | [MOL File]
101152-94-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
179-1810C | [Fp ]
9℃ | [storage temp. ]
2-8°C
| [solubility ]
H2O: 19 mg/mL
| [form ]
solid
| [color ]
white
| [Water Solubility ]
H2O: 19mg/mL | [Usage]
Antidepressant | [Merck ]
14,6194 | [InChI]
InChI=1/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15+;/s3 | [InChIKey]
XNCDYJFPRPDERF-DPKVYHSMNA-N | [SMILES]
[C@@]1(C(=O)N(CC)CC)(C[C@H]1CN)C1C=CC=CC=1.Cl |&1:0,9,r| | [CAS DataBase Reference]
101152-94-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301 | [Precautionary statements ]
P301+P310 | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
7-16-36/37-45 | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
GZ1014010
| [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29242990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral | [Toxicity]
LD50 orally in mice: 237 mg/kg (Bonnaud) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
antibacterial | [Uses]
Antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. | [Definition]
ChEBI: Milnacipran hydrochloride is a member of acetamides. | [General Description]
Milnacipran, sold under the brand names Savella?, Ixel?, Dalcipran?, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin. | [Biological Activity]
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo . | [Biochem/physiol Actions]
Serotonin and norepinephrine reuptake inhibitor (SNRI) | [storage]
+4°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 18918157536; |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Adamas Reagent, Ltd.
|
| Telephone: |
4006009262 13023226327 |
| Website: |
http://www.tansoole.com |
|