Back to ChemicalBook Home--->CAS DataBase List--->10416-59-8

10416-59-8

10416-59-8 Structure

10416-59-8 Structure
IdentificationMore
[Name]

N,O-Bis(trimethylsilyl)acetamide
[CAS]

10416-59-8
[Synonyms]

BIS(TRIMETHYLSILYL)ACETAMIDE
BSA
dynasylan bsa
N,O-BIS(TRIMETHYLSILYL)ACETAMIDE
TMS-BA
Trimethylsilyl N-trimethylsilylacetamidate
Acetimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester
bis(trimethylsllyl)acetamide
CB2500
Ethanimidicacid,N-(trimethylsilyl)-,trimethylsilylester
N-(Trimethylsilyl)acetimidic acid, trimethylsilyl ester
n-(trimethylsilyl)acetimidicacid,trimethylsilylester
n-(trimethylsilyl)-acetimidicacitrimethylsilylester
n-(trimethylsilyl)-ethanimidicacitrimethylsilylester
Trimethylsilyl (1E)-N-[(E)-trimethylsilyl]ethanimidoate
NO-Bis (trimethylsilyl) acetamide 90+ % gas chromatography
N.O-Bis(trimethylsilyl)acetamide (BSA)
N,O-BIS(TRIMETHYLSILYL)ACETAMIDE SET WIT H 10 X 1 ML
N,O-Bis(trimethyl-d9-silyl)acetamide (BSA-d18), 98% CP, 99 atom % D
N,O-BIS(TRIMETHYLSILYL)ACETAMIDE, FOR GC
[EINECS(EC#)]

233-892-7
[Molecular Formula]

C8H22NOSi2
[MDL Number]

MFCD00008270
[Molecular Weight]

204.44
[MOL File]

10416-59-8.mol
Chemical PropertiesBack Directory
[Appearance]

Clear to yellowish clear liquid
[mp ]

24 °C
[bp ]

71-73 °C35 mm Hg(lit.)
[density ]

0.832 g/mL at 20 °C(lit.)
[refractive index ]

n20/D 1.417(lit.)
[Fp ]

53 °F
[storage temp. ]

0-6°C
[Sensitive ]

Moisture Sensitive
[Detection Methods]

GC
[BRN ]

1306669
[CAS DataBase Reference]

10416-59-8(CAS DataBase Reference)
[NIST Chemistry Reference]

Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester(10416-59-8)
[EPA Substance Registry System]

10416-59-8(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

C,Xn,F
[Risk Statements ]

R10:Flammable.
R14:Reacts violently with water.
R22:Harmful if swallowed.
R34:Causes burns.
R40:Limited evidence of a carcinogenic effect.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S7/8:Keep container tightly closed and dry .
S36:Wear suitable protective clothing .
S30:Never add water to this product .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S16:Keep away from sources of ignition-No smoking .
S7/9:Keep container tightly closed and in a well-ventilated place .
[RIDADR ]

UN 2920 8/PG 2
[WGK Germany ]

3
[RTECS ]

AK3000000
[F ]

10-21
[TSCA ]

Yes
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29310095
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Toluene-->Chlorotrimethylsilane-->Acetamide-->Triethylamine hydrochloride
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Trimethylsilyl N-trimethylsilylacetamidate(10416-59-8).msds
Questions And AnswerBack Directory
[Description]

Clear to yellowish clear liquid liquid which is soluble in many nonpolar and polar aprotic solvents.
The trimethylsilyl group is a frequently utilized monofunctional blocking group for protic organic and inorganic materials. As it eliminated during the silylation is neutral acetamide, N,O-Bis(trimethylsilyl)acetamide can be preferably used for substrates which are acid- or base-sensitive.
N,O-bis(trimethylsilyl)-acetamide is an effective silylating agent. It is used in the pharmaceutical and in the chemical industry. Typically the silylating reaction with BSA results in neutral by-products only.
[Uses]

  1. Used for blocking and protection of hydroxyl groups in natural products, e.g. amino acids, carbohydrates;
  2. Used for blocking and protection of functional groups in organic intermediates;
  3. Used for formation of derivatives of H-acid compounds for analysis;
The silylated derivatives are volatile and can therefore be determined by gas chromatography. Deblocking is preferably carried out by means of hydrolysis, giving high yields. In some cases, thermal elimination of the trimethylsilyl group is possible.
Spectrum DetailBack Directory
[Spectrum Detail]

N,O-Bis(trimethylsilyl)acetamide(10416-59-8)MS
N,O-Bis(trimethylsilyl)acetamide(10416-59-8)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

N,O-Bis(trimethylsilyl)acetamide, 95%(10416-59-8)
[Alfa Aesar]

N,O-Bis(trimethylsilyl)acetamide, 95%(10416-59-8)
[Sigma Aldrich]

10416-59-8(sigmaaldrich)
[TCI AMERICA]

TMS-BA  [=N,O-Bis(trimethylsilyl)acetamide] (25% in Acetonitrile) [for Gas Chromatography](10416-59-8)
10416-59-8 suppliers list
Company Name: Win-Win Chemical CO., Limited
Tel: 0086-577-64498589
Fax: 0086-577-56994596
Website: www.win-winchemical.com
Company Name: Jinan Jianfeng Chemical Co., Ltd
Tel: 15562555968
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList31185/0.htm
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 (0)592-605 1114
Fax:
Website: www.amoychem.com
Company Name: Chemwill Asia Co.,Ltd.
Tel: 86-21-51086038
Fax: 86-21-51861608
Website: www.chemwill.com
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-188-71490254
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList31316/0.htm
Company Name: Haihang Industry Co.,Ltd
Tel: 86-531-88032799
Fax: +86 531 8582 1093
Website: www.haihangindustry.com
Company Name: Zjartschem
Tel: +86-571-8723 8903 jocelynpan@zjarts.com
Fax: +86-571-87063838
Website: www.zjartschem.com
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Fax: +86 21 5161 9052/ 5187 7796
Website: www.atkchemical.com
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Fax: 0371-55170693
Website: www.tianfuchem.net
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Fax:
Website: www.dakentech.com
Company Name: career henan chemical co
Tel: +86-371-86658258
Fax:
Website: www.coreychem.com
Company Name: NINGBO INNO PHARMCHEM CO., LTD.
Tel: 13867897135
Fax:
Website: www.en.nbinno.com
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Fax: +86-0592-6210733
Website: www.mainchem.com
Company Name: Tianjin Zhongxin Chemtech Co., Ltd.
Tel: 022-89880739
Fax: 022-66880086
Website: www.chemicalbook.com/ShowSupplierProductsList30693/0_EN.htm
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
Tel: 025-83697070;product@chemlin.com.cn
Fax:
Website: www.echemlin.cn
Company Name: Shanghai Time Chemicals CO., Ltd.
Tel: +86-021-57951555
Fax: +86-021-57951555
Website: www.time-chemicals.com
Company Name: Alfa Aesar  Gold
Tel:400-610-6006; 021-67582000
Fax:021-67582001/03/05
Website:www.alfachina.cn
Company Name: Zouping Mingxing Chemical Co.,Ltd.  Gold
Tel:13605431940
Fax:0086-0543-2240079
Website:www.zoutong.com.cn
Tags:10416-59-8 Related Product Information
18162-48-6 60-35-5 13435-12-6 25561-30-2 10416-59-8 103-90-2 127-19-5 107-91-5 62-55-5