| Identification | Back Directory | [Name]
SB 242084 (hydrochloride) | [CAS]
1049747-87-6 | [Synonyms]
CAS 1049747-87-6
SB-242084 HCl salt
SB 242084 (hydrochloride)
SB242084;SB 242084;CAS 1049747-87-6 | [Molecular Formula]
C21H21Cl3N4O2 | [MOL File]
1049747-87-6.mol | [Molecular Weight]
467.776 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Ethanol:1.0(Max Conc. mg/mL);2.14(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);21.38(Max Conc. mM)
DMSO:59.63(Max Conc. mg/mL);127.47(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);64.13(Max Conc. mM) | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that activates specific receptors located primarily in the gut and central nervous system. SB-242084 is an antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors. In vivo, it is brain penetrant and has significant anxiolytic activity, without sedative, proconvulsant, or hyperphagic properties. SB-242084 has been used extensively in animal research to evaluate, for example, 5-HT2C receptor agonists and neurotransmitter receptor interactions in mice. | [Uses]
SB 242084 Hydrochloride is an antagonist of the SR-2C. | [Definition]
ChEBI: 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide;dihydrochloride is an organic molecular entity, an indole alkaloid and a pyridine. It has a role as a receptor modulator. | [storage]
Desiccate at +4°C |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
|