| Identification | Back Directory | [Name]
(D-ALA1)-PEPTIDE T AMIDE | [CAS]
106362-34-9 | [Synonyms]
DAPTA
Adaptavir
DAPTA(TFA)
DAPTA?, >98%
Octapeptide T
Adaptavir (DAPTA)
D-Ala-peptide T-amide
(D-ALA1)-PEPTIDE T AMIDE
(D-Ala1)-Peptide T aMide
DAPTA
D-ALA-SER-THR-THR-THR-ASN-TYR-THR-NH2
H-D-ALA-SER-THR-THR-THR-ASN-TYR-THR-NH2
D-ala-ser-thr-thr-thr-asn-tyr-thr amide acetate
D-Ala-L-Ser-L-Thr-L-Thr-L-Thr-L-Asn-L-Tyr-L-Thr-NH2
DAPTA,ASTTTNYT,D-Ala-peptide T-amide,Adaptavir, >98%
(D-Ala1)-Peptide T amide H-D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-NH2
L-ThreoninaMide, D-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-
(2S)-N-[(2S)-1-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]butanediamide | [Molecular Formula]
C35H56N10O15 | [MDL Number]
MFCD00076838 | [MOL File]
106362-34-9.mol | [Molecular Weight]
856.88 |
| Chemical Properties | Back Directory | [Boiling point ]
1514.3±65.0 °C(Predicted) | [density ]
1.415±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
H2O : 50 mg/mL (58.35 mM; Need ultrasonic) | [form ]
Powder | [pka]
9.82±0.15(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-NH2 |
| Hazard Information | Back Directory | [Uses]
DAPTA is a chemokine receptor 5 (CCR5) antagonist used as a selective viral entry inhibitor for R5 tropic HI-1 strains. Blocks CCR5-mediated monocyte chemotaxis. | [IC 50]
HIV-1; gp120BaL/sCD4-CCR5: 55 pM (IC50, in Cf2Th/synR5 cells); gp120CMCM235/sCD4-CCR5: 0.32 nM (IC50, in Cf2Th/synR5 cells) | [storage]
Desiccate at -20°C |
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