| Identification | Back Directory | [Name]
Histatin 5 | [CAS]
115966-68-2 | [Synonyms]
Human histatin 5
Peptide F-A (human parotid saliva)
Histatin 5 (synthetic human re-Hst5)
L-Tyrosine, L-α-aspartyl-L-seryl-L-histidyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-histidylglycyl-L-tyrosyl-L-lysyl-L-arginyl-L-lysyl-L-phenylalanyl-L-histidyl-L-α-glutamyl-L-lysyl-L-histidyl-L-histidyl-L-seryl-L-histidyl-L-arginylglycyl- | [Molecular Formula]
C133H195N51O33 | [MDL Number]
MFCD00210682 | [MOL File]
115966-68-2.mol | [Molecular Weight]
3036.29 |
| Hazard Information | Back Directory | [Uses]
Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. | [storage]
Store at -20°C | [References]
[1] Gusman H, et al. Salivary histatin 5 is an inhibitor of both host and bacterial enzymes implicated in periodontaldisease. Infect Immun. 2001 Mar;69(3):1402-8. DOI:10.1128/IAI.69.3.1402-1408.2001
[2] Helmerhorst EJ, et al. The human salivary peptide histatin 5 exerts its antifungal activity through the formation ofreactive oxygen species. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14637-42. DOI:10.1073/pnas.141366998 |
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CHEMICAL LAND21
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