| Identification | More | [Name]
N-BOC-4-Hydroxypiperidine | [CAS]
109384-19-2 | [Synonyms]
1-BOC-4-HYDROXYPIPERIDINE
1-BOC-4-PIPERIDINOL
1-PIPERIDINECARBOXYLIC ACID, 4-HYDROXY-,1,1-DIMETHYLETHYL ESTER
1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE
1-TERT-BUTOXYCARBONYL-4-PIPERIDINOL
4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
BOC-(4-HYDROXY)-PIPERIDINE
N-BOC-4-HYDROXYLPIPERIDINE
N-BOC-4-HYDROXYPIPERIDINE
N-BOC-4-PIPERIDINOL
N-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE
N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL
RARECHEM AH CK 0055
TERT-BUTYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE
TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE
1-N-Boc-4-hydroxypiperidine
TERT-BUTYL 4-HYDROXY-1-PIPERIDINE-CARBOX
4-Hydroxypiperidine, N-BOC protected 98+%
1-BOC-4-HYDROXYLPIPERIDINE
1-BOC-4-HYDROXYPIPERIDINE/1-TERT-BUTOXYCARBONYL-4-HYDROXYPIPERIDINE | [EINECS(EC#)]
600-916-6 | [Molecular Formula]
C10H19NO3 | [MDL Number]
MFCD01075174 | [Molecular Weight]
201.26 | [MOL File]
109384-19-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White to cream powder | [Melting point ]
61-65 °C (lit.) | [Boiling point ]
292.3±33.0 °C(Predicted) | [density ]
1.107±0.06 g/cm3(Predicted) | [storage temp. ]
Store at-15°C | [solubility ]
Chloroform, Ethyl Acetate | [form ]
Powder | [pka]
14.80±0.20(Predicted) | [color ]
White to cream | [Detection Methods]
MP,NMR | [BRN ]
7202094 | [InChI]
InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3 | [InChIKey]
PWQLFIKTGRINFF-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC(O)CC1 | [CAS DataBase Reference]
109384-19-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29333990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White to cream powder | [Uses]
N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds. | [Preparation]
A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).
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