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111072-31-2

111072-31-2 Structure

111072-31-2 Structure
IdentificationMore
[Name]

XTT sodium salt
[CAS]

111072-31-2
[Synonyms]

SODIUM 3,3'-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]BIS (4-METHOXY-6-NITRO)BENZENE SULFONIC ACID HYDRATE
SODIUM-3,3-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]-BIS(4-METHOXY-6-NITRO)BENZENE SULPHONIC ACID HYDRATE
XTT
xttsodium
XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide)
XTT SODIUM CELL CULTURE TESTED
XTT SODIUM SALT CELL CULTURE REAGENT 90%
XTT SODIUM SALT 90%
XII SODIUM
50mg
Sodium-3,3-{1-[(phenylamino)carbonyl]-3,4-tetrazolium}-bis(4-methoxy-6-nitro)benzenesulphonicacidhydrate
(2,3-Bis-(2-Methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide)
SODIUM 2,3-BIS(2-METHOXY-4-NITRO-5-SULFOPHENYL)-2H-TETRAZOLIUM-5-CARBOXANILIDE INNER SALT
Tetrazolium XTT
XTT sodium salt
2,3-Bis(2-methoxy-4-nitro-5-sulphophenyl)-2H-tetrazolium-5-carboxanilide inner salt
5-(Phenylaminocarbonyl)-2-(2-methoxy-4-nitro-5-sodiooxysulfonylphenyl)-3-(2-methoxy-4-nitro-5-sulfonatophenyl)-2H-tetrazol-3-ium
[EINECS(EC#)]

601-039-1
[Molecular Formula]

C22H18N7NaO13S2
[MDL Number]

MFCD00191206
[Molecular Weight]

675.54
[MOL File]

111072-31-2.mol
Chemical PropertiesBack Directory
[Melting point ]

285 ℃ (decompose)
[storage temp. ]

2-8°C
[solubility ]

hot water: 2.5 mg/mL
[form ]

powder
[color ]

Yellow
[Water Solubility ]

Soluble in hot water at 2.5mg/ml.Soluble in water, dimethyl sulfoxide, dimethyl formamide and phosphate buffered saline.at pH =7.2.
[λmax]

286 nm
[Biological Applications]

Cell proliferation assays; cytotoxicity assays; ecotoxicity assays; neurotoxicity assays; antimicrobial susceptibility testing assays; antifungal susceptibility testing assays; cardiac valve viability assays; cell viability assay
[CAS DataBase Reference]

111072-31-2(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[HS Code ]

29339900
Hazard InformationBack Directory
[Uses]

Tetrazolium derivative useful in cancer research.XTT sodium salt is used in conjunction with phenazine methosulfate to screen human cancer cell lines. It is also used to study fungal cell damage. It is involved in testing antimicrobial susceptibility of staphylococci and in candida biofilm research. Further, it is used in an assay for cell viability and cell proliferation.
[General Description]

XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is a tetrazolium salt, which forms water-soluble formazan on bioreduction.
[Biochem/physiol Actions]

XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is acted upon by dehydrogenases present in metabolically active cells. This produces water soluble formazan, which is a highly colored product. Thus, it offers an advantage in colorimetric proliferation assays, as opposed to MTT, as the product is already soluble and no formazan crystals are formed.
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

111072-31-2(sigmaaldrich)
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