| Identification | More | [Name]
Disodium edetate dihydrate | [CAS]
6381-92-6 | [Synonyms]
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID
BETZ 0640
COMPLEXONE II(R)
EDATHAMIL
EDETIC ACID
EDTA
EDTA ACID
EDTA REAGENT
EDTA SOLUTION
EDTA TITRANT
ETHYLENEBIS(IMINODIACETIC ACID)
ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID
ETHYLENEDIAMINETETRAACETIC ACID
ETHYLENEDIAMINETETRACETIC ACID
(ETHYLENEDINITRILO)TETRAACETIC ACID
HAMPENE ACID
IDRANAL(R)
TIMTEC-BB SBB008807
TITRIPLEX II
TITRIPLEX II EDTA | [EINECS(EC#)]
205-358-3 | [Molecular Formula]
C10H18N2Na2O10 | [MDL Number]
MFCD00003541 | [Molecular Weight]
372.24 | [MOL File]
6381-92-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
250 °C (dec.)(lit.)
| [Boiling point ]
>100 °C
| [density ]
1.01 g/mL at 25 °C
| [FEMA ]
4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT | [refractive index ]
n20/D 1.363
| [Fp ]
>100℃ | [storage temp. ]
2-8°C
| [solubility ]
3 M NaOH: 100 mg/mL
| [form ]
crystalline
| [pka]
pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C) | [color ]
≤5 (0.5 M)(APHA)
| [Odor]
Odorless | [PH]
4.0-5.5 (25℃, 0.1M in H2O) | [PH Range]
4 - 5 at 10 g/l at 23 °C | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
soluble | [λmax]
λ: 260 nm Amax: 0.145
λ: 280 nm Amax: 0.025 | [BRN ]
3900609 | [InChIKey]
QCDUWWPHAVXXQS-UHFFFAOYSA-L | [CAS DataBase Reference]
6381-92-6(CAS DataBase Reference) | [EPA Substance Registry System]
6381-92-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36:Irritating to the eyes.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R36/38:Irritating to eyes and skin .
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
2
| [RTECS ]
AH4025000
| [F ]
3 | [TSCA ]
Yes | [HS Code ]
29224995 | [Toxicity]
LD50 orally in Rabbit: > 2000 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white, crystalline powder. | [Uses]
Chelating agent; sequestering agent | [Uses]
Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant. | [Definition]
ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt. | [General Description]
Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases. | [Biochem/physiol Actions]
Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases. | [Purification Methods]
Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.] |
|
|