| Identification | Back Directory | [Name]
yemuoside YM(10) | [CAS]
114902-16-8 | [Synonyms]
yemuoside
yemuoside YM
yemuoside YM(10)
CIWUJIANOSIDE B (RG)
acanthopanax senticosides B
Ciwujianoside B, 98%, from Acanthopanax senticosus (Rupr. & Maxim.) Harms
30-Noroleana-12,20(29)-dien-28-oicacid, 3-[[2-O-(6-deoxy-a-L-mannopyranosyl)-a-L-arabinopyranosyl]oxy]-, O-6-deoxy-a-L-mannopyranosyl-(14)-O-b-D-glucopyranosyl-(16)-b-D-glucopyranosyl ester, (3b)-
30-Noroleana-12,20(29)-dien-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)- | [Molecular Formula]
C58H92O25 | [MDL Number]
MFCD10566605 | [MOL File]
114902-16-8.mol | [Molecular Weight]
1189.34 |
| Chemical Properties | Back Directory | [density ]
1.48 | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
12.50±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ciwujianoside B is isolated from Eleutherococcus senticosus leaf, is able to penetrate and work in the brain after the oral administration. Ciwujianoside B significantly enhances object recognition memory[1].
Ciwujianoside B shows radioprotective effects on the hematopoietic system in mice, which is associated with changes in the cell cycle, reduces DNA damage and down-regulates the ratio of Bax/Bcl-2 in bone marrow cells exposed to radiation[2]. | [References]
[1] Yamauchi Y, et al. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain. Nutrients. 2019 May 22;11(5). pii: E1142. DOI:10.3390/nu11051142
[2] Li YR, et al. Comparative investigations on the protective effects of rhodioside, ciwujianoside-B and astragaloside IV on radiation injuries of the hematopoietic system in mice. Phytother Res. 2011 May;25(5):644-53. DOI:10.1002/ptr.3313 |
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