| Identification | More | [Name]
N6-Cbz-L-Lysine | [CAS]
1155-64-2 | [Synonyms]
EPSILON-CARBOBENZOXY-L-LYSINE
H-LYS(CBZ)-OH
H-LYS(Z)-OH
L-LYSINE(CBZ)
LYSINE(Z)-OH
LYS(Z)
N(5)-BENZYLOXYCARBONYL-L-LYSINE
N6-CARBOBENZYLOXY-L-LYSINE
N-BENZYLOXYCARBONYL-L-LYSINE
N(EPSILON)-BENZYLOXYCARBONYL-L-LYSINE
NEPSILON-CARBOBENZOXY-L-LYSINE
N-EPSILON-CARBOBENZYLOXY-L-LYSINE
N-EPSILON-CBZ-L-LYSINE
N-EPSILON-CBZ-LYSINE
N-EPSILON-Z-L-LYSINE
N6-Carbobenzyloxy-L-lysine
N6-benzyloxycarbonyl-L-lysine
N6-Cbz-L-Lysine
N-6-CARBOBENZYLOXY-L-LYSINE 98%
N-EPSILON-CBZ-L-LYSINE 98+% | [EINECS(EC#)]
214-585-7 | [Molecular Formula]
C14H20N2O4 | [MDL Number]
MFCD00002638 | [Molecular Weight]
280.32 | [MOL File]
1155-64-2.mol |
| Questions And Answer | Back Directory | [Synthesis]
The conventional synthetic method for N6-Cbz-L-lysine starts with the corresponding configuration of lysine and an acyl chloride from another segment, reacting the amino group and the acyl chloride to generate the corresponding amide to obtain the target product N6-Cbz-L-lysine. This route requires the addition of an external base as an acid-binding agent, such as sodium hydroxide. 
|
| Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
259 °C (dec.)(lit.)
| [alpha ]
14.4 º (c=1.6 in 1N HCl) | [Boiling point ]
423.04°C (rough estimate) | [density ]
1.1429 (rough estimate) | [refractive index ]
16 ° (C=1.6, 2mol/L HCl) | [storage temp. ]
-20°C | [solubility ]
Aqueous Base, Dilute Acid | [form ]
Powder | [pka]
2.53±0.24(Predicted) | [color ]
White to off-white | [Optical Rotation]
[α]20/D +15.5±1°, c = 1% in 1 M HCl | [BRN ]
2222482 | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C14H20N2O4/c15-12(13(17)18)8-4-5-9-16-14(19)20-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,15H2,(H,16,19)(H,17,18)/t12-/m0/s1 | [InChIKey]
CKGCFBNYQJDIGS-LBPRGKRZSA-N | [SMILES]
C(O)(=O)[C@H](CCCCNC(OCC1=CC=CC=C1)=O)N | [CAS DataBase Reference]
1155-64-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29242990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Uses]
Protected amino acid | [reaction suitability]
reaction type: solution phase peptide synthesis |
|
| Company Name: |
AF Biochem Co., Ltd. Gold
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+86-028-60911900 13540204019 |
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www.afbiochem.com |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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