| Identification | Back Directory | [Name]
N3-PEG10-N3 | [CAS]
1171122-72-7 | [Synonyms]
N3-PEG10-N3
1,29-diazido-3,6,9,12,15,18,21,24,27-nonaoxanonacosane
Inhibitor,inhibit,PROTAC Linkers,AzidoPEG9azide,Azido PEG9 azide,Azido-PEG-9-azide | [Molecular Formula]
C20H40N6O9 | [MDL Number]
MFCD34470093 | [MOL File]
1171122-72-7.mol | [Molecular Weight]
508.57 |
| Hazard Information | Back Directory | [Uses]
Azido-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG9-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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