ChemicalBook--->CAS DataBase List--->117294-21-0

117294-21-0

117294-21-0 Structure

117294-21-0 Structure
IdentificationBack Directory
[Name]

8-Bromo-2-tetralone
[CAS]

117294-21-0
[Synonyms]

8B2T
8-broMo-3
8-BROMO-2-TETRALONE
8-Bromotetralin-2-one
8-Bromo-3,4-dihydro-1H-phthalen-2-one
8-BROMO-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE
8-BROMO-3,4-DIHYDRO-2(1H)-NAPHTHALENONE
2(1H)-Naphthalenone, 8-bromo-3,4-dihydro-
8-BroMo-1,2,3,4-tetrahydro-2-oxonaphthalene
[Molecular Formula]

C10H9BrO
[MDL Number]

MFCD03093390
[MOL File]

117294-21-0.mol
[Molecular Weight]

225.08
Questions And AnswerBack Directory
[Synthesis]

The target compound, 8-Bromo-2-tetralone, was prepared by cyclization reaction using o-bromophenylacetic acid and 2-bromophenylacetyl chloride as starting materials. The synthetic reaction formula for 8-Bromo-2-tetralone is shown in the figure below:

Synthesis of 117294-21-0

[Uses]

As a tetrahydronaphthone compound, 8-bromo-3,4-dihydro-1H-2-naphthone is an important intermediate in the synthesis of selective 5-HT6 receptor antagonists, which have the potential to treat central nervous system disorders such as Parkinson's disease.
Chemical PropertiesBack Directory
[Boiling point ]

331.0±42.0 °C(Predicted)
[density ]

1.511±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
[HazardClass ]

IRRITANT
Spectrum DetailBack Directory
[Spectrum Detail]

8-Bromo-2-tetralone(117294-21-0)1HNMR
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