| Identification | More | [Name]
4,6-Dihydroxypyrimidine | [CAS]
1193-24-4 | [Synonyms]
4(1H)-PYRIMIDINONE, 6-HYDROXY-
4,6-DIHYDROXYPYRIMIDINE
4,6-PYRIMIDINEDIOL
6-Hydroxy-1H-pyrimidin-4-one
AURORA KA-5482
4,6-dihydroxypyrimidin
6-hydroxy-4(1h)-pyrimidinon
6-hydroxy-4(1H)-Pyrimidinone
4(1H)-Pyrimidinone, 6-hydroxy-(8CI,9CI)
4,6-Dihydroxy
6-Hydroxy-1H-pyrimidin-4-on
Pyrimidine-4,6-diol
4,6-DIHYDROXYPYRIMIDINE/4,6-PYRIMIDINEDIOL
4,6-Dioxypyrimidine
6-Hydroxy-3H-pyrimidin-4-one
6-Hydroxy-4(1H)-pyrimidone
6-Hydroxypyrimidine-4(1H)-one
6-Hydroxypyrimidine-4(3H)-one | [EINECS(EC#)]
214-772-3 | [Molecular Formula]
C4H4N2O2 | [MDL Number]
MFCD00016733 | [Molecular Weight]
112.09 | [MOL File]
1193-24-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Yellow Powder | [Melting point ]
>300 °C (lit.) | [Boiling point ]
209.98°C (rough estimate) | [density ]
1.4421 (rough estimate) | [vapor pressure ]
0.001Pa at 20℃ | [refractive index ]
1.4610 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
2.5 g/L (20° C) | [form ]
Powder | [pka]
5.70±0.10(Predicted) | [color ]
Yellow to orange | [Water Solubility ]
2.5 g/L (20 º C) | [Detection Methods]
HPLC,NMR | [BRN ]
606433 | [InChI]
1S/C4H4N2O2/c7-3-1-4(8)6-2-5-3/h1-2H,(H2,5,6,7,8) | [InChIKey]
DUFGYCAXVIUXIP-UHFFFAOYSA-N | [SMILES]
Oc1cc(O)ncn1 | [LogP]
-2.8 at 25℃ | [CAS DataBase Reference]
1193-24-4(CAS DataBase Reference) | [NIST Chemistry Reference]
4(1H)-pyrimidinone, 6-hydroxy-(1193-24-4) | [EPA Substance Registry System]
1193-24-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
1
| [RTECS ]
UW7523000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29335995 | [Storage Class]
11 - Combustible Solids |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Sodium Methoxide-->Diethyl malonate-->Formamide-->MALONIC ACID DI-N-BUTYL ESTER-->formamide-->Dimethyl malonate-->Hydrochloric acid-->Water-->Methanol | [Preparation Products]
Bensulfuron methyl-->4,5-Diaminopyrimidine-->4,6-DIAMINO-5-NITROPYRIMIDINE-->Chlorimuron-ethyl-->4,6-Dichloropyrimidine-->6-CHLORO-5-NITROPYRIMIDIN-4-AMINE-->6-AMINO-5-NITROPYRIMIDIN-4-OL-->5-Amino-4,6-dichloropyrimidine-->ETRIMFOS-->4,6-Dichloro-5-nitropyrimidine-->4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE-->4-CHLORO-6-HYDRAZINO-PYRIMIDIN-5-YLAMINE-->5-AMINO-6-CHLORO-PYRIMIDIN-4-OL-->2-Amino-4,6-dichloropyrimidine-->5-Bromo-4,6-dichloropyrimidine-->4,6-Dichloro-5-pyrimidinecarbaldehyde-->4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE-->4,6-DIHYDROXY-5-NITROPYRIMIDINE-->2-(methylthio)pyrimidine-4,6-diol-->5-Bromo-4,6-dihydroxypyrimidine |
| Hazard Information | Back Directory | [Chemical Properties]
Light Yellow Powder | [Uses]
4,6-Dihydroxypyrimidine (cas# 1193-24-4) is a compound useful in organic synthesis. | [Definition]
ChEBI: 4,6-dihydroxypyrimidine is a hydroxypyrimidine. | [Flammability and Explosibility]
Notclassified | [Synthesis]
Synthesis of 4,6-dihydroxypyrimidine (DHP) by reaction of a malonic acid ester with formamide and an alkali metal alkoxide at elevated temperature. | [References]
[1] Patent: CN106883186, 2017, A. Location in patent: Paragraph 0037; 0038; 0039; 0040; 0041; 0042; 0043-0052
[2] Patent: CN105859637, 2016, A. Location in patent: Paragraph 0020; 0021; 0022 |
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