| Identification | Back Directory | [Name]
BIG ET-1 (1-38) (HUMAN) | [CAS]
120796-97-6 | [Synonyms]
ENDOTHELIN, BIG, HUMAN
BIG ET-1 (1-38) (HUMAN)
BIG ENDOTHELIN 38 HUMAN
BIG ENDOTHELIN-1 (HUMAN)
Endothelin 1 (human),big
ENDOTHELIN, BIG 1-38, HUMAN
BIG-ENDOTHELIN-I (1-38), HUMAN
BIG ENDOTHELIN-1 (HUMAN, 1-38)
BIG ENDOTHELIN-1 (1-38) (HUMAN)
BIG ET-1 (1-38) (HUMAN) USP/EP/BP
CSCSSLMDKECVYFCHLDIIWVNIPEHWPYGLGSPRS
CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS
CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER
H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER-OH
CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR- PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser (Disulfide bridges Cys1-Cys15 and Cys3-Cys11) | [Molecular Formula]
C189H282N48O56S5 | [MDL Number]
MFCD00081408 | [Molecular Weight]
4282.87 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [Sequence]
Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser (Disulfide bridge: Cys1-Cys15; Cys3-Cys11) |
| Hazard Information | Back Directory | [Uses]
Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide[1]. | [References]
[1] Marie-Hélène Fecteau, et al. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension. 2005 Jul;46(1):87-92. DOI:10.1161/01.HYP.0000170460.24604.23 |
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