ChemicalBook--->CAS DataBase List--->1264-62-6

1264-62-6

1264-62-6 Structure

1264-62-6 Structure
IdentificationBack Directory
[Name]

Erythromycin ethylsuccinate
[CAS]

1264-62-6
[Synonyms]

Esinol
Evesin
Refkas
Anamycin
Arpimycin
E-Mycin e
Eryliquid
Sigapedil
Monomycin
Wyamycin E
Erythro ES
erythroped
Durapaediat
Erythro-Holz
Paediathrocin
Erythromycin ethyl s
erythrocinethylsuccinate
ErythroMycin ethyl succina
ERYTHROMYCIN ETHYLSUCCINATE
ERYTHROMYCIN ETHLY SUCCINATE.
ERYTHROMYCINETHYLSUCCINATE,USP
ErythroMycin Ethylsuccinate API
ERYTHROMYCIN ETHYISUCCINATE USP
erythromycin,mono(ethylsuccinate)
ERYTHROMYCIN 2'-(ETHYL SUCCINATE)
Erythromycin ethyl succinate (6CI)
ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE)
Erythromycin Ethylsuccinate (200 mg)
Oxacyclotetradecane, erythromycin deriv.
erythromycin,mono(ethylsuccinate)(ester)
Erythromycin, 2'-(ethyl succinate) (7CI)
Succinic acid, monoester with erythromycin
ERYTHROMYCIN ETHYLSUCCINATE EPE(CRM STANDARD)
ERYTHROMYCIN ETHYLSUCCINATE USP(CRM STANDARD)
Erythromycin 2''-[3-(ethoxycarbonyl)propionate]
Erythromycin, mono(ethyl succinate) (ester) (8CI)
succinicacid,monoethylester,monoesterwitherythromycin
Succinic acid, ethyl ester, monoester with erythromycin (8CI)
Ethyl [(2R,3S,4R,6S)-4-dimethylamino-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-6-methyl-oxan-3-yl] butanedioate
[EINECS(EC#)]

215-033-8
[Molecular Formula]

C43H75NO16
[MDL Number]

MFCD00084692
[MOL File]

1264-62-6.mol
[Molecular Weight]

862.05
Chemical PropertiesBack Directory
[Melting point ]

219-224 C
[Boiling point ]

778.19°C (rough estimate)
[density ]

1.1417 (rough estimate)
[refractive index ]

1.5280 (estimate)
[Fp ]

>110°(230°F)
[storage temp. ]

2-8°C
[solubility ]

ethanol: soluble50mg/mL
[form ]

solid
[pka]

13.09±0.70(Predicted)
[color ]

white
[Water Solubility ]

Freely soluble in organic solvents, practically insoluble in water
[Stability:]

Hygroscopic
[CAS DataBase Reference]

1264-62-6
Hazard InformationBack Directory
[Chemical Properties]

crystals
[Uses]

antibacterial
[Brand name]

E-Mycin (Pharmacia & Upjohn); E.E.S. (Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin (Wyeth).
[General Description]

Erythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2'-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether.
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

42/43-36/37/38
[Safety Statements ]

36-26
[WGK Germany ]

2
[RTECS ]

WM9800000
[HS Code ]

29419000
[Hazardous Substances Data]

1264-62-6(Hazardous Substances Data)
[Toxicity]

LD50 oral in mouse: > 10gm/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Tetrahydrofuran-->Succinic anhydride-->Erythromycin
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Erythromycin ethylsuccinate (1264-62-6).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Erythromycin ethylsuccinate(1264-62-6)MS
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