| Identification | More | [Name]
5-Bromo-2-methoxy-6-picoline | [CAS]
126717-59-7 | [Synonyms]
2-METHOXY-5-BROMO-6-PICOLINE
2-METHYL-3-BROMO-6-METHOXY PYRIDINE
3-BROMO-6-METHOXY-2-METHYLPYRIDINE
3-BROMO-6-METHOXY-2-PICOLINE
5-Bromo-2-Methoxy-6-Methylpyridine | [Molecular Formula]
C7H8BrNO | [MDL Number]
MFCD03094943 | [Molecular Weight]
202.05 | [MOL File]
126717-59-7.mol |
| Chemical Properties | Back Directory | [Boiling point ]
86°C/10mmHg(lit.) | [density ]
1.468g/mLat 25℃ | [refractive index ]
n20/D 1.548 | [Fp ]
106°C | [storage temp. ]
2-8°C | [form ]
Liquid | [pka]
1.76±0.10(Predicted) | [color ]
Colorless | [InChI]
InChI=1S/C7H8BrNO/c1-5-6(8)3-4-7(9-5)10-2/h3-4H,1-2H3 | [InChIKey]
VWNXCCTWVAQAPL-UHFFFAOYSA-N | [SMILES]
C1(C)=NC(OC)=CC=C1Br | [CAS DataBase Reference]
126717-59-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
41-22 | [Safety Statements ]
26-39 | [WGK Germany ]
3 | [HazardClass ]
IRRITANT | [HS Code ]
2933399990 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1 |
| Hazard Information | Back Directory | [Synthesis]
A mixture of 5-bromo-6-methyl-1H-pyridin- 2-one (5.5 g, 29 mmol), silver carbonate (10.89 g, 39 mmol), iodomethane (13.6 mL, 217 mmol) and chloroform (115 mL) is stirred overnight in the dark at room temperature. Triethylamine (10 mL) is added, and stirring is continued for 1.5 hr. The reaction mixture is filtered through a pad of Hi-Flo, and the filtrate is washed with water (100 mL), dried, filtered and concentrated. The residue is purified by filtration through a pad of silica gel washing with cyclohexane-20percent ethyl acetate. The solvent is concentrated to afford 3-Bromo-6-methoxy-2-picoline (3.7 g, 63percent yield) as an oil. | [References]
[1] Patent: WO2005/51954, 2005, A2. Location in patent: Page/Page column 39; 40 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
Tetranov Biopharm
|
| Telephone: |
13526569071 |
| Website: |
http://www.leadmedpharm.com/index.html |
|