| Identification | More | [Name]
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate | [CAS]
128625-52-5 | [Synonyms]
1H-BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE
1H-BENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE
(BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINPHOSPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOL-1-YLOXYTRIS(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
BENZOTRIAZOLE-1-YL-OXY-TRIS-DIMETHYLAMINOPHOPHONIUM
BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM
BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRRORIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE
BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHYLAMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE)
BOP
BOPP
BOP REAGENT
CASTROS REAGENT
CASTRO'S REAGENT
HEXAFLUOROPHOSPHATE BOP | [EINECS(EC#)]
260-279-1 | [Molecular Formula]
C18H28F6N6OP2 | [MDL Number]
MFCD00011948 | [Molecular Weight]
520.39 | [MOL File]
128625-52-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
154-156 °C (dec.)(lit.)
| [density ]
1.438 at 20℃ | [vapor pressure ]
0-0Pa at 20-50℃ | [storage temp. ]
2-8°C
| [solubility ]
methanol: 25 mg/mL, clear
| [form ]
Fine Crystalline Powder | [color ]
White to off-white | [Sensitive ]
Moisture Sensitive | [Detection Methods]
NMR | [BRN ]
3584612 | [InChIKey]
BYCLGHOAELJLOF-UHFFFAOYSA-M | [LogP]
-0.3 at 26℃ and pH3.5-3.7 | [CAS DataBase Reference]
128625-52-5(CAS DataBase Reference) | [Storage Precautions]
Moisture sensitive;Light sensitive |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R37/38:Irritating to respiratory system and skin .
R44:Risk of explosion if heated under confinement.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 1325 4.1/PG 2
| [WGK Germany ]
3
| [F ]
8-10-21 | [Hazard Note ]
Irritant | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
One of the most convenient coupling reagents for peptide synthesis without carcinogenic by-products. It replaces BOP reagent. This is especially suitable for solid-phase peptide synthesis, avoids racemization. | [General Description]
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation. |
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