| Identification | Back Directory | [Name]
3-(2-(2-bromoethoxy)ethoxy)prop-1-yne | [CAS]
1287660-82-5 | [Synonyms]
Propargyl-PEG2-Br
Propargyl-PEG2-bromide
3-(2-(2-bromoethoxy)ethoxy)prop-1-yne
1-Propyne, 3-[2-(2-bromoethoxy)ethoxy]- | [Molecular Formula]
C7H11BrO2 | [MDL Number]
MFCD24465329 | [MOL File]
1287660-82-5.mol | [Molecular Weight]
207.07 |
| Hazard Information | Back Directory | [Uses]
Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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