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1287660-82-5

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1287660-82-5 Structure

1287660-82-5 Structure
IdentificationBack Directory
[Name]

3-(2-(2-bromoethoxy)ethoxy)prop-1-yne
[CAS]

1287660-82-5
[Synonyms]

Propargyl-PEG2-Br
Propargyl-PEG2-bromide
3-(2-(2-bromoethoxy)ethoxy)prop-1-yne
1-Propyne, 3-[2-(2-bromoethoxy)ethoxy]-
[Molecular Formula]

C7H11BrO2
[MDL Number]

MFCD24465329
[MOL File]

1287660-82-5.mol
[Molecular Weight]

207.07
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335-H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard InformationBack Directory
[Uses]

Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

3-(2-(2-bromoethoxy)ethoxy)prop-1-yne(1287660-82-5)1HNMR
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