| Identification | Back Directory | [Name]
Ald-Ph-PEG4-acid | [CAS]
1309460-27-2 | [Synonyms]
Ald-peg4-acid
Ald-Ph-PEG4-COOH
Ald-Ph-PEG4-acid
CHO-Ph-PEG4-acid
Ald-Ph-amido-PEG4-C2-acid
1-(4-formylphenyl)-1-oxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oic acid
Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]- | [Molecular Formula]
C19H27NO8 | [MDL Number]
MFCD18916985 | [MOL File]
1309460-27-2.mol | [Molecular Weight]
397.42 |
| Chemical Properties | Back Directory | [Boiling point ]
628.8±55.0 °C(Predicted) | [density ]
1.216±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Viscous Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
Ald-Ph-PEG4-acid is a small molecule PEG reagent. The benzaldehyde group is reactive with hydrazide and aminooxy moiety. The terminal carboxylic acid can couple with primary amines in the presence of activators such as EDC or HATU to form a stable amide bond. The hydrophilic PEG linker increases the solubility of compounds in aqueous media. | [Uses]
Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC). | [IC 50]
Non-cleavable Linker |
|
|