| Identification | Back Directory | [Synonyms]
CHO-PEG5-COOtBu
Ald-CH2-PEG5-Boc
CHOCH2-PEG5-COOtBu
Ald-PEG5-t-butyl ester
Ald-CH2-PEG5-CH2CH2COOtBu
ALD-CH2-PEG5-T-BUTYL ESTER
4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-oxo-, 1,1-dimethylethyl ester | [Molecular Weight]
364.43 |
| Hazard Information | Back Directory | [Description]
Ald-CH2-PEG5-t-butyl ester is an aldehyde PEG linker that is reactive with aminooxy-containing molecules. The t-butyl ester can be removed under acidic conditions for further conjugation.PEG5 spacer of the compound arimproves aqueous solubility. | [Uses]
Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034. DOI:10.1021/acschembio.9b00505 |
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