ChemicalBook--->CAS DataBase List--->1334-78-7

1334-78-7

1334-78-7 Structure

1334-78-7 Structure
IdentificationBack Directory
[Name]

TOLUALDEHYDES
[CAS]

1334-78-7
[Synonyms]

tolyl
TOLUALDEHYDE
TOLUALDEHYDES
ar-Tolualdehyde
METHYLBENZALDEHYDE
tolualdehydes, mixture
TOLUALDEHYDES USP/EP/BP
TOLUALDEHYDES (MIXED O,M,P)
TOLUALDEHYDES(MIXEDORTHO,META,PARA)
[EINECS(EC#)]

215-615-1
[Molecular Formula]

C7H6O
[MDL Number]

MFCD00212759
[MOL File]

1334-78-7.mol
[Molecular Weight]

106.122
Chemical PropertiesBack Directory
[Boiling point ]

164.15°C (rough estimate)
[density ]

0.9651 (rough estimate)
[FEMA ]

3068 | TOLUALDEHYDES (MIXED O,M,P)
[refractive index ]

1.4800 (estimate)
[Odor]

at 1.00 % in dipropylene glycol. sweet cherry chemical coumarin powdery
[Odor Type]

fruity
[JECFA Number]

866
[Cosmetics Ingredients Functions]

PERFUMING
[LogP]

2.26
[EPA Substance Registry System]

Methylbenzaldehyde (1334-78-7)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Xylene
[Preparation Products]

leather seasoning agent DLC-1-->Acitretin
Safety DataBack Directory
[TSCA ]

TSCA listed
[Hazardous Substances Data]

1334-78-7(Hazardous Substances Data)
[Toxicity]

LD50 oral in rat: 2250mg/kg
Hazard InformationBack Directory
[Chemical Properties]

Colorless liquid. Slightly soluble inwater; soluble in alcohol and ether. There are also oand misomers. Combustible.
[Chemical Properties]

Tolualdehydes, mixed o-, m-, p-, have a sweet and herbaceous odor reminiscent of bitter almond.
[Occurrence]

Reported found in roasted nuts, tomato, cooked beef, beef fat, cider, coffee, tea and elderberry juice.
[Uses]

Perfumes, pharmaceutical and dyestuff intermediate, flavoring agent.
[Preparation]

By oxidation of o-, m-, or p-xylene (chemical or electrolytical oxidation).
[Taste threshold values]

Taste characteristics at 15 ppm: cherry pit, coumarin, almond, sweet, with a slight powdery hay and vanillalike nuance.
[Metabolism]

Aromatic aldehydes are oxidized in vivo almost entirely to the corresponding acid. Thus, in rabbits, p-tolualdehyde is converted to p-toluic acid which has been detected in the urine as the ester glucuronide (Williams, 1959). p-Tolualdehyde was oxidized to p-toluic acid by resting cells of Pseudomonas aeruginosa (Omori & Yamada, 1970). Perillaldehyde dehydrogenase, isolated from a soil pseudomonad, catalysed the oxidation of m- and p-tolualdehyde but not of o-tolualdehyde (Ballal, Bhattacharyya & Rangachari, 1967). The reduction of p-tolualdehyde by NADH was catalysed by horse-liver alcohol dehydrogenase (Blomquist, 1966) and by yeast alcohol dehydrogenase at pH 8.5-9.5 (Klinman, 1975). A non-specific NADPH-linked aldehyde reductase isolated from various areas of bovine brain also catalysed the reduction of p-tolualdehyde (Tabakoff & Erwin, 1970).
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