| Identification | Back Directory | [Name]
sinapultide | [CAS]
138531-07-4 | [Synonyms]
ATI 01
RWJ 45652
sinapultide
KL4 (peptide)
sinapultide USP/EP/BP
L-Lysine, L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl- | [Molecular Formula]
C126H238N26O22 | [MDL Number]
MFCD18251732 | [MOL File]
138531-07-4.mol | [Molecular Weight]
2469.4 |
| Chemical Properties | Back Directory | [Boiling point ]
2047.1±65.0 °C(Predicted) | [density ]
1.093 | [form ]
Solid | [pka]
3.31±0.10(Predicted) | [color ]
White to off-white | [Sequence]
H-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-OH | [InChIKey]
QSIRXSYRKZHJHX-TWXHAJHVSA-N |
| Hazard Information | Back Directory | [Uses]
Pulmonary surfactant. | [Synthesis]
The Protect 21 peptide resin was transferred to a 2000 ml reactor, add the reagent (TFA/TIS=932 ml/68 ml) which was prepared beforehand and pre-cooled to about -10 to -7°C, and stirred at 13-16°C for 65 minutes. The solvent was removed to a small volume u | [in vivo]
Sinapultide-loaded microbubbles (MBs) (0.1 mg; nasal delivery; collected at 3, 6, 12 and 24 hours after LPS) improves pulmonary edema in lung injury and increases lung W/D weight in LPS-induced ALI mice[2].
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