| Identification | More | [Name]
Tiotropium bromide hydrate | [CAS]
139404-48-1 | [Synonyms]
(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate
(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide
(1R,2R,4S,5S,7S)-7-[2-HYDROXY-2,2-DI(2-THIENYL)ACETOXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4] NONANE BROMIDE MONOHYDRATE
TIOTROPIUM BROMIDE
tiotropium bromide hydrate
TIOTROPIUM BROMIDE MONOHYDRATE
TIOTROPIUM BROMDIE
Tiotropium
(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate
(1R,2R,4S,5S,7S)-7-[2-HYDROXY-2,2-DI(2-THIENYL)ACETOXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4] NONANE BROMIDE MONOHYDRATE | [EINECS(EC#)]
690-508-4 | [Molecular Formula]
C19H22BrNO4S2.H2O | [MDL Number]
MFCD00867027 | [Molecular Weight]
490.43 | [MOL File]
139404-48-1.mol |
| Hazard Information | Back Directory | [Chemical Properties]
White or yellowish-white powder or crystals. | [Uses]
Tiotropium Bromide hydrate is a hydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Although tiotropium Bromide (Spiriva; Tiova; BA 679BR; tiopropium) doe | [Definition]
ChEBI: Tiotropium bromide hydrate is a hydrate that is the monohydrate form of tiotropium bromide. Used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist and a bronchodilator agent. | [Clinical Use]
Maintenance treatment of chronic obstructive pulmonary disease | [Drug interactions]
Potentially hazardous interactions with other drugs
Avoid administration with other anti-cholinergic
drugs.
Anti-arrhythmics: increased risk of antimuscarinic
side effects with disopyramide. | [Metabolism]
Tiotropium is excreted largely unchanged in the urine, although it may undergo some metabolism by non-enzymatic cleavage and by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4. |
|
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
Adamas Reagent, Ltd.
|
| Telephone: |
4006009262 13023226327 |
| Website: |
http://www.tansoole.com |
| Company Name: |
Shanghai Ennopharm Co., Ltd.
|
| Telephone: |
+86 (21) 6435-5022 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList13640/0_EN.htm |
|