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14009-24-6

14009-24-6 Structure

14009-24-6 Structure
IdentificationMore
[Name]

Drotaverin hydrochloride
[CAS]

14009-24-6
[Synonyms]

1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl) methylene)-isoquinoline hydrochloride
1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride
1-[(3,4-DIETHOXYPHENYL)METHYLENE]-6,7-DIETHOXY 1,2,3,4-TETRAHYDROISOQUINOLINE HCL
(1z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-3,4-dihydro-2h-isoquinoline hydrochloride
6,7,3',4'-tetraethoxy-1-benzal-1,2,3,4-tetrahydroisoquinoline hydrochloride
DROTAVERINE
DROTAVERINE HCL
DROTAVERINE HYDROCHLORIDE
drotaverin hydrochloride
isodihydroperparine hydrochloride
drotaverin
Drotaverine&Int.
1-(3,4-Diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline
1-[(3,4-Diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline
[EINECS(EC#)]

604-171-8
[Molecular Formula]

C24H31NO4.HCl
[MDL Number]

MFCD00347721
[Molecular Weight]

433.97
[MOL File]

14009-24-6.mol
Chemical PropertiesBack Directory
[Boiling point ]

520.94°C (rough estimate)
[density ]

1.1507 (rough estimate)
[refractive index ]

1.6000 (estimate)
[pka]

6.17±0.20(Predicted)
[Water Solubility ]

13.75g/L(37 ºC)
[InChI]

InChI=1S/C24H31NO4/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20/h9-10,13-16,25H,5-8,11-12H2,1-4H3
[InChIKey]

OMFNSKIUKYOYRG-UHFFFAOYSA-N
[SMILES]

C1(=CC2=CC=C(OCC)C(OCC)=C2)C2=C(C=C(OCC)C(OCC)=C2)CCN1
[CAS DataBase Reference]

14009-24-6(CAS DataBase Reference)
Hazard InformationBack Directory
[Uses]

Drotaverine is a selective phosphodiesterase 4 inhibitor with angina relief activity. Drotaverine is used to suppress angina, including pain in the gastrointestinal tract and biliary tract. Drotaverine may also cause compound-induced priapism, a side effect of sustained penile erection[1].
[Definition]

ChEBI: Drotaverine is a member of isoquinolines.
[References]

[1] Drotaverine-induced priapism DOI:10.4103/iju.IJU_240_20
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