| Identification | More | [Name]
Drotaverin hydrochloride | [CAS]
14009-24-6 | [Synonyms]
1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl) methylene)-isoquinoline hydrochloride 1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride 1-[(3,4-DIETHOXYPHENYL)METHYLENE]-6,7-DIETHOXY 1,2,3,4-TETRAHYDROISOQUINOLINE HCL (1z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-3,4-dihydro-2h-isoquinoline hydrochloride 6,7,3',4'-tetraethoxy-1-benzal-1,2,3,4-tetrahydroisoquinoline hydrochloride DROTAVERINE DROTAVERINE HCL DROTAVERINE HYDROCHLORIDE drotaverin hydrochloride isodihydroperparine hydrochloride drotaverin Drotaverine&Int. 1-(3,4-Diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline 1-[(3,4-Diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline | [EINECS(EC#)]
604-171-8 | [Molecular Formula]
C24H31NO4.HCl | [MDL Number]
MFCD00347721 | [Molecular Weight]
433.97 | [MOL File]
14009-24-6.mol |
| Chemical Properties | Back Directory | [Boiling point ]
520.94°C (rough estimate) | [density ]
1.1507 (rough estimate) | [refractive index ]
1.6000 (estimate) | [pka]
6.17±0.20(Predicted) | [Water Solubility ]
13.75g/L(37 ºC) | [InChI]
InChI=1S/C24H31NO4/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20/h9-10,13-16,25H,5-8,11-12H2,1-4H3 | [InChIKey]
OMFNSKIUKYOYRG-UHFFFAOYSA-N | [SMILES]
C1(=CC2=CC=C(OCC)C(OCC)=C2)C2=C(C=C(OCC)C(OCC)=C2)CCN1 | [CAS DataBase Reference]
14009-24-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Drotaverine is a selective phosphodiesterase 4 inhibitor with angina relief activity. Drotaverine is used to suppress angina, including pain in the gastrointestinal tract and biliary tract. Drotaverine may also cause compound-induced priapism, a side effect of sustained penile erection[1]. | [Definition]
ChEBI: Drotaverine is a member of isoquinolines. | [References]
[1] Drotaverine-induced priapism DOI:10.4103/iju.IJU_240_20 |
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