| Identification | More | [Name]
(R)-N-Boc-3-aminomethylpiperidine | [CAS]
140645-23-4 | [Synonyms]
(R)-1-BOC-3-(AMINOMETHYL)PIPERIDINE
(R)-1-N-BOC-3-(AMINOMETHYL)PIPERIDINE
(R)-1-N-BOC-PIPERIDINE-3-METHYLAMINE
(R)-3-AMINOMETHYL-1-N-BOC-PIPERIDINE
(R)-3-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
(R)-N-BOC-3-AMINOMETHYLPIPERIDINE
(R)-TERT-BUTYL 3-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE
1,1-dimethyl (3R)-3-(aminomethyl)-1-piperidinecarboxylate
3-(Aminomethyl)-1-Boc-piperidine
3-Aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
tert-Butyl 3-(aminomethyl)piperidine-1-carboxylate
(R)-3-(Aminomethyl)piperidine, N1-BOC protected | [Molecular Formula]
C11H22N2O2 | [MDL Number]
MFCD03839876 | [Molecular Weight]
214.3 | [MOL File]
140645-23-4.mol |
| Questions And Answer | Back Directory | [Uses]
(R)-1-Boc-3-aminomethylpiperidine is an important intermediate in the synthesis of many drugs. A series of checkpoint kinase 1 (CHK1) inhibitors have been synthesized using (R)-1-Boc-3-aminomethylpiperidine as a starting material, showing some efficacy in treating rheumatoid arthritis. A series of drugs for treating diseases related to MCH (melanin-concentrating hormone) have also been synthesized using this compound, showing some effectiveness in treating metabolic disorders. G-protein-coupled receptor (GPCR) agonists containing the 1-N-Boc-4-methylaminomethylpiperidine structural unit have been synthesized, which can be used to treat obesity and diabetes. A series of drugs for regulating metabolism and treating cardiovascular diseases have also been synthesized using (R)-1-Boc-3-aminomethylpiperidine. |
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