| Identification | Back Directory | [Name]
5-Aminolevulinic acid hexyl ester hydrochloride | [CAS]
140898-91-5 | [Synonyms]
Hexvix
P 1206
Hexaminolevulinate HCl
ALA HEXYL ESTER HYDROCHLORIDE
AMINOLEVULINC ACID HEXYL ESTER
Hexaminolevulite hydrochloride
HexaMinolevulinate hydrochloride
Hexyl 5-aMinolevulinate hydrochloride
N-HEXYL 5-AMINOLEVULINATE HYDROCHLORIDE
Hexyl 5-amino-4-oxopentanoate hydrochloride
AMINOLEVULINIC ACID HEXYL ESTER HYDROCHLORIDE
Hexaminolevulinate hydrochloride >=98% (HPLC)
Hex-1-yl 5-amino-4-oxopentanoate hydrochloride
5-AMINOLEVULINIC ACID HEXYL ESTER HYDROCHLORIDE
DELTA-AMINOLEVULINIC ACID HEXYL ESTER HYDROCHLORIDE
5-AMINO-4-OXOPENTANOIC ACID HEXYL ESTER HYDROCHLORIDE
3-AMinoacetylpropionic acid hexyl ester hydrochloride
Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride
Pentanoic acid, 5-aMino-4-oxo-, hexyl ester, hydrochloride (9CI)
Hex-1-yl 5-aminolevulinate hydrochloride, Hex-1-yl 5-amino-4-oxovalerate hydrochloride
HEXYL 5-AMINOLEVULINATE HYDROCHLORIDE; P-1206; 5-AMINOLEVULINIC ACID HEXYL ESTER HYDROCHLORIDE
Hexyl 5-AMinolevulinate hydrochloride,3-AMinoacetylpropionic acid hexyl ester hydrochloride,Hexyl 5-aMino-4-oxopentanoate Hexyl 5-AMinolevulinate hydrochloride | [Molecular Formula]
C11H22ClNO3 | [MDL Number]
MFCD03695491 | [MOL File]
140898-91-5.mol | [Molecular Weight]
251.75 |
| Chemical Properties | Back Directory | [Melting point ]
94° | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO:41.0(Max Conc. mg/mL);162.86(Max Conc. mM) | [form ]
A solid | [color ]
White to off-white | [Appearance]
Solid Powder | [Water Solubility ]
H2O: 20mg/mL, clear | [Sensitive ]
Light Sensitive/Hygroscopic | [Cosmetics Ingredients Functions]
SKIN CONDITIONING | [InChI]
InChI=1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H | [InChIKey]
LZYXPFZBAZTOCH-UHFFFAOYSA-N | [SMILES]
C(=O)(OCCCCCC)CCC(=O)CN.Cl |
| Hazard Information | Back Directory | [Description]
Hexaminolevulinate is a lipophilic, hexyl ester prodrug form of 5-aminolevulinic acid. It produces equivalent protoporphyrin IX (PpIX) induction in WiDr and NHIK 3025 carcinoma cells at concentrations approximately 100-fold lower than 5-aminolevulinic acid. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). | [Uses]
Diagnostic agent for the diagnosis of bladder cancer. | [Biological Activity]
Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA)a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALAand is 50–100 times more efficient than ALA at inducing PpIXwhich accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancerin particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis. |
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| Company Name: |
Henan Alpha Chemical Co., Ltd.
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| Telephone: |
0371-55055611 18137792234 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList31206/0.htm |
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