| Identification | Back Directory | [Name]
BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER | [CAS]
142439-92-7 | [Synonyms]
BIOTIN DSHSE
NHS-SS-11-Biotin
(+)-Biotin-SS-NHS
Biotin-bisamido-SS-NHS
Biotin-bisamido-SS-NHS ester
BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER
SucciniMidyl 2-(biotinaMido)-ethyl-1,3' -dithiopropionate
Succinimidyl 3-[3-[2-(biotinamido)ethyl]amino-3-oxopropyl]dithio]propionate
[2-(BIOTINAMIDO)ETHYLAMIDO]-3,3'-DITHIODIPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER
(3aS,4S,6aR)-N-[2-[[3-[[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-1-oxopropyl]amino]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[[3-[[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-1-oxopropyl]amino]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- | [Molecular Formula]
C22H33N5O7S3 | [MDL Number]
MFCD00466919 | [MOL File]
142439-92-7.mol | [Molecular Weight]
575.72 |
| Chemical Properties | Back Directory | [Melting point ]
129-131°C | [density ]
1.43 | [storage temp. ]
−20°C | [solubility ]
DMF: 50 mg/mL | [form ]
powder | [pka]
13.90±0.40(Predicted) | [InChIKey]
LWPHUVGDBNUVHA-GXZWQRSESA-N | [SMILES]
[H][C@]12CS[C@@H](CCCCC(=O)NCCNC(=O)CCSSCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2 |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
61 | [Safety Statements ]
53-23-36/37/39-45 | [WGK Germany ]
1 | [HS Code ]
29349990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Repr. 1B |
| Hazard Information | Back Directory | [Description]
Biotin-bisamido-SS-NHS is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. The cross-bridge and extended spacer arm are helpful in minimizing steric hindrance involved with the binding to avidin or streptavidin probes. This biotin compound is membrane-permeable and useful for intracellular labeling. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label. | [Uses]
NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups
in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT. | [Uses]
NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT. | [IC 50]
Alkyl/ether |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|