| Identification | More | [Name]
3-Chloro-4-fluorophenylboronic acid | [CAS]
144432-85-9 | [Synonyms]
3-CHLORO-4-FLUOROBENZENEBORONIC ACID
3-CHLORO-4-FLUOROPHENYLBORONIC ACID
4-FLUORO-3-CHLOROPHENYLBORONIC ACID
AKOS BRN-0032
RARECHEM AH PB 0129
3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) | [EINECS(EC#)]
675-657-5 | [Molecular Formula]
C6H5BClFO2 | [MDL Number]
MFCD00051800 | [Molecular Weight]
174.37 | [MOL File]
144432-85-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-white to faintly orange powder | [Melting point ]
242-247 °C (lit.) | [Boiling point ]
306.0±52.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator (+4°C) | [solubility ]
soluble in Methanol | [form ]
Powder | [pka]
7?+-.0.10(Predicted) | [color ]
Off-white to faintly orange | [BRN ]
7369789 | [InChI]
1S/C6H5BClFO2/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,10-11H | [InChIKey]
WJDZZXIDQYKVDG-UHFFFAOYSA-N | [SMILES]
OB(O)c1ccc(F)c(Cl)c1 | [CAS DataBase Reference]
144432-85-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29163990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white to faintly orange powder | [Uses]
Reactant for:
- Rh-catalyzed asymmetric addition reactions
- Palladium-catalyzed oxidative cross-coupling reaction
- Suzuki-Miyaura coupling
| [Uses]
3-Chloro-4-fluorophenylboronic Acid is a reactant that has been used in the synthesis of 2-bromo-3-hexyl-5-(4-iodophenyl)thiophene, which has shown high anti-thrombolytic activity. | [Uses]
suzuki reaction |
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