| Identification | More | [Name]
3-Chlorophenylboronic acid | [CAS]
63503-60-6 | [Synonyms]
3-CHLOROBENZENEBORONIC ACID
3-CHLOROPHENYLBORNIC ACID
3-CHLOROPHENYLBORONIC ACID
AKOS BRN-0010
M-CHLOROPHENYLBORONIC ACID
RARECHEM AH PB 0179
3-CHLOROBENZENEBORONIC ACID/3-CHLOROPHENYLBORONIC ACID
3-CHLOROPHENYLBORONIC ACID 98%
3-Chlorophenylboronic Acid (contains varying amounts of Anhydride) | [EINECS(EC#)]
628-786-6 | [Molecular Formula]
C6H6BClO2 | [MDL Number]
MFCD00161354 | [Molecular Weight]
156.37 | [MOL File]
63503-60-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow-green crystalline powder or | [Melting point ]
185-189 °C(lit.)
| [Boiling point ]
311.4±44.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
0-6°C | [solubility ]
soluble in Methanol | [form ]
Crystalline Powder or Needles | [pka]
7.55±0.10(Predicted) | [color ]
White to light yellow-green | [Water Solubility ]
Slightly soluble in water. soluble in ether, tetrahydrofuran,, dimethyl sulfoxide, dimethyl formamide, methanol. | [BRN ]
2936343 | [InChI]
InChI=1S/C6H6BClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4,9-10H | [InChIKey]
SDEAGACSNFSZCU-UHFFFAOYSA-N | [SMILES]
B(C1=CC=CC(Cl)=C1)(O)O | [CAS DataBase Reference]
63503-60-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302+H312+H332 | [Precautionary statements ]
P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29319099 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow-green crystalline powder or | [Uses]
suzuki reaction | [Synthesis]
Using m-dichlorobenzene as the starting material, iodine particles and 1,2-dibromoethane as the initiator reacts with magnesium in an organic solvent to prepare 3-chlorophenyl magnesium chloride. Then, the trimethyl borate is reacted with an organic solvent to prepare 3-chlorophenyl borate dimethyl ester. Finally, the product 3-chlorophenylboronic acid is obtained through hydrolysis, extraction, and crystallization. | [Solubility in organics]
3-Chlorophenylboronic acid can be dissolved in organic solvents such as N, N-dimethylformamide, ethyl acetate, and dichloromethane. In addition, it also has specific solubility in low-polarity and non-polar organic solvents, but 3-chlorophenylboronic acid has poor solubility in water. | [References]
[1] European Journal of Medicinal Chemistry, 2017, vol. 126, p. 590 - 603
[2] Organic Letters, 2005, vol. 7, # 21, p. 4757 - 4759
[3] Tetrahedron, 2007, vol. 63, # 35, p. 8529 - 8536 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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