| Identification | Back Directory | [Name]
(Z)-Mutagenic Impurity of Tenofovir Disoproxil | [CAS]
1464851-21-5 | [Synonyms]
Tenofovir Impurity 59
(Z)-9-Propenyladenine
9-[(Z)-1-Propenyl]-9H-purine-6-amine
9H-Purin-6-amine, 9-(1Z)-1-propen-1-yl-
(Z)-9-(prop-1-en-1-yl)-9H-purin-6-amine
(Z)-Mutagenic Impurity of Tenofovir Disoproxil | [Molecular Formula]
C8H9N5 | [MDL Number]
MFCD30718180 | [MOL File]
1464851-21-5.mol | [Molecular Weight]
175.19 |
| Chemical Properties | Back Directory | [Boiling point ]
415.6±48.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: ≥ 100 mg/mL (570.81 mM) | [form ]
Solid | [pka]
4.08±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral agent known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. | [IC 50]
HIV-1 |
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