ChemicalBook--->CAS DataBase List--->148-51-6

148-51-6

148-51-6 Structure

148-51-6 Structure
IdentificationMore
[Name]

4-Deoxypyridoxine hydrochloride
[CAS]

148-51-6
[Synonyms]

4-DEOXYPYRIDOXINE HCL
4-DEOXYPYRIDOXINE HYDROCHLORIDE
5-HYDROXY-4,6-DIMETHYL-3-PYRIDINEMETHANOL HYDROCHLORIDE
DEOXYPYRIDOXINE, 4-HCL
4,6-dimethyl-5-hydroxy-3-pyridinemethanohydrochloride
4-deoxypyridoxolhydrochloride
5-hydroxy-4,6-dimethyl-3-pyridinemethanohydrochloride
desoxypyridoximehydrochloride
nsc3063
3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridinium chloride
4-deoxypyridoxine hydrochloride*crystalline
5-(Hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride
Deoxypyridoxine hydrochloride
[EINECS(EC#)]

205-714-8
[Molecular Formula]

C8H12ClNO2
[MDL Number]

MFCD00051296
[Molecular Weight]

189.64
[MOL File]

148-51-6.mol
Chemical PropertiesBack Directory
[Melting point ]

274°C(dec.)(lit.)
[storage temp. ]

−20°C
[form ]

neat
[CAS DataBase Reference]

148-51-6(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

UT4800000
[HS Code ]

29333990
[Toxicity]

LD50 oral in chicken: 1570mg/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Palladium-->Pyridoxal phosphate
Hazard InformationBack Directory
[Description]

4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.
[Chemical Properties]

Solid
[Uses]

4-Deoxypyridoxine is the deoxy analogue of Pyridoxine (P991735). 4-Deoxypyridoxine is a vitamin B6 antimetabolite; 4-Deoxypyridoxine can induce a deficient status that alters the function and ultrastructure of EC similar to vascular disease.
Spectrum DetailBack Directory
[Spectrum Detail]

4-Deoxypyridoxine hydrochloride(148-51-6)MS
4-Deoxypyridoxine hydrochloride(148-51-6)IR1
4-Deoxypyridoxine hydrochloride(148-51-6)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

148-51-6(sigmaaldrich)
[TCI AMERICA]

4-Deoxypyridoxine Hydrochloride,>98.0%(LC)(T)(148-51-6)
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