| Identification | More | [Name]
2,5-Dimethylpyridine | [CAS]
589-93-5 | [Synonyms]
2,5-DIMETHYLPYRIDINE
25L
2,5-LUTIDINE
2,5-dimethyl-pyridin
5-methyl-2-methylpyridine
pyridine,2,5-dimethyl-
2,5-LUTIDINE 98+%
a,d-Dimethylpyridine
2,5-DIMETHYLPYRIDINE, 2,5-LUTIDINE | [EINECS(EC#)]
209-666-9 | [Molecular Formula]
C7H9N | [MDL Number]
MFCD00006343 | [Molecular Weight]
107.15 | [MOL File]
589-93-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
−15 °C(lit.)
| [Boiling point ]
157 °C(lit.)
| [density ]
0.926 g/mL at 25 °C(lit.)
| [vapor pressure ]
2.4 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.499(lit.)
| [Fp ]
118 °F
| [form ]
clear liquid | [pka]
6.4(at 25℃) | [color ]
Colorless to Light orange to Yellow | [Water Solubility ]
77g/L(23 ºC) | [Specific Heat Capacity]
Cp(liquid):184.7J/(g·K),at 25℃ | [Sensitive ]
Hygroscopic | [Henry's Law Constant]
1.1×100 mol/(m3Pa) at 25℃, Andon et al. (1954) | [InChI]
1S/C7H9N/c1-6-3-4-7(2)8-5-6/h3-5H,1-2H3 | [InChIKey]
XWKFPIODWVPXLX-UHFFFAOYSA-N | [SMILES]
Cc1ccc(C)nc1 | [LogP]
1.708 (est) | [CAS DataBase Reference]
589-93-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Pyridine, 2,5-dimethyl-(589-93-5) | [EPA Substance Registry System]
589-93-5(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS02,GHS07 | [Signal word ]
Warning | [Hazard statements ]
H226-H302+H312+H332-H315-H319-H335 | [Precautionary statements ]
P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338 | [Hazard Codes ]
Xn,F,Xi | [Risk Statements ]
R10:Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [RTECS ]
OK9625000
| [TSCA ]
TSCA listed | [HazardClass ]
3.2 | [PackingGroup ]
III | [HS Code ]
2933399990 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
2,5-Dimethylpyridine is a colorless liquid, it is flammable and stable under recommended storage conditions.
| [Uses]
2,5-Lutidine was used to displace CO from the haem iron. | [Synthesis Reference(s)]
Tetrahedron Letters, 17, p. 383, 1976 DOI: 10.1016/S0040-4039(00)93738-9 | [General Description]
The FT-IR and FT-Raman spectra of 2,5-lutidine was studied. | [Hazard]
2,5-Dimethylpyridine is acute toxicity.
| [Purification Methods]
Steam distil the lutidine from a solution containing 1-2 equivalents of 20% H2SO4 until about 10% of the base has been carried over with the non-basic impurities, then the acidic solution is made alkaline, and the base is separated, dried with NaOH and fractionally distilled twice. Dry the distillate with Na and fractionally distil it through a Todd column (p 11) packed with glass helices. The hydrochloride has m 219o(dec), and the picrate has m 170.5o (from EtOH or H2O). [Beilstein 20 H 244, 20 II 160, 20 III/IV 2774, 20/6 V 27.] |
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