| Identification | Back Directory | [Name]
2',4',6',3,4-PENTAHYDROXYCHALCONE | [CAS]
14917-41-0 | [Synonyms]
PENTADECANE, n-(RG)
ERIODICTYOL CHALCONE
3,4,2',4',6'-PENTAHYDROXYCHALCONE
2',4',6',3,4-PENTAHYDROXYCHALCONE
PENTAHYDROXYCHALCONE,2',4',6',3,4-
PENTAHYDROXYCHALCONE,2',4',6',3,4-(SH)
3,4,2'',4'',6''-PENTAHYDROXYCHALCONE WITH HPLC
(E)-3-(3,4-Dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
(2E)-3-(3,4-Dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-propen-1-one
2-Propen-1-one,3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, (2E)- | [Molecular Formula]
C15H12O6 | [MDL Number]
MFCD00017302 | [MOL File]
14917-41-0.mol | [Molecular Weight]
288.25 |
| Chemical Properties | Back Directory | [Melting point ]
157-158 °C | [Boiling point ]
595.908±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.584±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
2-8°C | [pka]
6.879±0.40(predicted) | [InChI]
InChI=1S/C15H12O6/c16-9-6-13(20)15(14(21)7-9)11(18)4-2-8-1-3-10(17)12(19)5-8/h1-7,16-17,19-21H/b4-2+ | [InChIKey]
CRBYNQCDRNZCNX-DUXPYHPUSA-N | [SMILES]
C(C1=C(O)C=C(O)C=C1O)(=O)/C=C/C1=CC=C(O)C(O)=C1 | [LogP]
2.680 (est) |
| Hazard Information | Back Directory | [Uses]
Eriodictyol chalcone possesses both anti-aromatase and an anti-17β-HSD activity[1]. | [Definition]
ChEBI: 2',3,4,4',6'-pentahydroxychalcone is a member of the class of chalcones that is chalcone substituted by hydroxy groups at positions 2', 3, 4, 4', and 6'. It is functionally related to a chalcone. It is a conjugate acid of a 2',3,4,4',6'-pentahydroxychalcone(1-). | [IC 50]
Aromatase | [References]
[1] J C Le Bail, et al. Chalcones are potent inhibitors of aromatase and 17beta-hydroxysteroid dehydrogenase activities. Life Sci. 2001 Jan 5;68(7):751-61. DOI:10.1016/s0024-3205(00)00974-7 |
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