| Identification | More | [Name]
trans-Chalcone | [CAS]
614-47-1 | [Synonyms]
1,3-DIPHENYL-2-PROPEN-1-ONE
1,3-DIPHENYL-2-PROPEN-I-ONE
1,3-DIPHENYL-2-PROPENONE
1,3-DIPHENYL-3-PROPEN-1-ONE
1,3-DIPHENYLPROP-2-EN-1-ONE
2-BENZALACETOPHENONE
2-BENZYLIDENEACETOPHENONE
(2E)-1,3-DIPHENYLPROP-2-EN-1-ONE
3-PHENYLACRYLOPHENONE
BENZALACETOPHENONE
BENZYLIDENEACETOPHENONE
BENZYLIDINEACETOPHENONE
CHALCONE
CHALKONE
(E)-CHALCONE
PHENYL STYRYL KETONE
TRANS-BENZYLIDENEACETOPHENONE
TRANS-CHALCONE
(e)-1,3-diphenyl-2-propen-1-one
(e)-benzylideneacetophenone | [EINECS(EC#)]
202-330-2 | [Molecular Formula]
C15H12O | [MDL Number]
MFCD00003082 | [Molecular Weight]
208.26 | [MOL File]
614-47-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
55-59 °C
| [Boiling point ]
208 °C25 mm Hg(lit.)
| [density ]
1.0712 | [refractive index ]
1.5361 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly) | [form ]
Solid | [color ]
Pale Yellow | [Odor]
at 100.00 %. floral balsam herbal | [Odor Type]
floral | [Water Solubility ]
Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water. | [Merck ]
14,2037 | [BRN ]
509985 | [LogP]
4.013 (est) | [CAS DataBase Reference]
614-47-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzalacetophenone(614-47-1) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37:Irritating to eyes and respiratory system . | [Safety Statements ]
S22:Do not breathe dust .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
3
| [RTECS ]
UD5576750
| [HS Code ]
29143990 |
| Hazard Information | Back Directory | [Description]
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer. | [Uses]
trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity. | [Application]
trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O). | [Definition]
ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones. | [Preparation]
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones | [Synthesis Reference(s)]
Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058 | [General Description]
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer. | [Biological Activity]
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots. | [Biochem/physiol Actions]
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots. |
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