| Identification | Back Directory | [Name]
AC-YVAD-PNA | [CAS]
149231-66-3 | [Synonyms]
AC-YVAD-PNA
ACETYL-YVAD-PNA
ICE SUBSTRATE IV
Caspase-1 Substrate IV
AC-TYR-VAL-ALA-ASP-PNA
REF DUPL: Ac-Tyr-Val-Ala-Asp-pNA
CASPASE-1 SUBSTRATE (CHROMOGENIC)
AC-TYR-VAL-ALA-ASP-PNA: AC-YVAD-PNA
AC-TYR-VAL-ALA-ASP-PARANITROANILIDE
CASPASE-1 SUBSTRATE IV, COLORIMETRIC
IL-1B CONVERTING ENZYME SUBSTRATE IV
ACETYL-TYR-VAL-ALA-ASP-(P-NITROANILIDE)
N-acetyl-tyr-val-ala-asp P-nitroanilide
CASPASE 1 (ICE) SUBSTRATE 2, CHROMOGENIC
N-ACETYL-TYR-VAL-ALA-ASP-P-NITROANILIDE PNA
IL-1BETA CONVERTING ENZYME (ICE) COLORIMETRIC SUBSTRATE
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-a-asparagine
L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)- | [Molecular Formula]
C29H36N6O10 | [MDL Number]
MFCD00274387 | [MOL File]
149231-66-3.mol | [Molecular Weight]
628.63 |
| Chemical Properties | Back Directory | [Boiling point ]
1108.9±65.0 °C(Predicted) | [density ]
1.362±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
powder | [pka]
4.04±0.10(Predicted) | [color ]
white to beige | [Sequence]
Ac-Tyr-Val-Ala-Asp-{pNA} | [InChIKey]
YDPNOCSPPGFBPX-XNHCRPTKSA-N | [SMILES]
O=C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC1=CC=C(O)C=C1)=O)=O)=O)NC2=CC=C([N+]([O-])=O)C=C2 |
| Hazard Information | Back Directory | [Uses]
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4. | [Biological Activity]
Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide)which can be quantified spectrophotometrically at 405 nm. | [IC 50]
Caspase-1 |
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| Company Name: |
Binhai gill polypeptide co. LTD
|
| Telephone: |
021-61263389 13524856427 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList326362/0_EN.htm |
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