| Identification | Back Directory | [Name]
AC-LEU-GLU-THR-ASP-AFC | [CAS]
210345-02-1 | [Synonyms]
AC-LETD-AFC
AC-LEU-GLU-THR-ASP-AFC
AC-LEU-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN
N-ACETYL-LEU-GLU-THR-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN
N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine
L-α-Asparagine,N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)
4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoicacid | [Molecular Formula]
C31H38F3N5O12 | [MDL Number]
MFCD07780890 | [MOL File]
210345-02-1.mol | [Molecular Weight]
729.65 |
| Hazard Information | Back Directory | [Description]
Ac-LETD-AFC is a fluorogenic substrate for caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. | [Uses]
N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine is a caspase substrate that is cleaved by caspase-8. | [Excitation / Emission Maximum]
400 nm/505 nm | [Sequene]
Ac-Leu-Glu-Thr-Asp-Unk |
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