| Identification | Back Directory | [Name]
Hydroxy-PEG2-CH2CO2t-Bu | [CAS]
149299-82-1 | [Synonyms]
HO-PEG2-CH2COOtBu
OH-PEG2-CH2COOtBu
Hydroxy-PEG2-CH2-Boc
Hydroxy-PEG2-CH2COOtBu
Hydroxy-PEG2-CH2CO2t-Bu
tert-butyl 2-(2-(2-hydroxyethoxy)ethoxy)acetate
2-(2-hydroxyethoxy)ethoxy]aceticacidtert-butylester
Acetic acid, [2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester
Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester | [Molecular Formula]
C10H20O5 | [MDL Number]
MFCD25959245 | [MOL File]
149299-82-1.mol | [Molecular Weight]
220.26 |
| Chemical Properties | Back Directory | [Boiling point ]
306.1±22.0 °C(Predicted) | [density ]
1.062±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [pka]
14.35±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Hydroxy-PEG2-CH2CO2tBu is a PEG linker containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | [Uses]
Hydroxy-PEG2-CH2CO2tBu was a useful reagent in the study for potentiator-corrector agonist of cystic fibrosis mutant protein ΔF508-CFTR preparation. |
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