| Identification | Back Directory | [Name]
Ganoderic acid AM1 | [CAS]
149507-55-1 | [Synonyms]
Ganoderic acid AM1
(3beta)-3-Hydroxy-7,11,15,23-tetraoxolanost-8-en-26-oic acid
Lanost-8-en-26-oicacid, 3-hydroxy-7,11,15,23-tetraoxo-, (3b)-
Lanost-8-en-26-oic acid, 3-hydroxy-7,11,15,23-tetraoxo-, (3β)- | [Molecular Formula]
C30H42O7 | [MDL Number]
MFCD21364032 | [MOL File]
149507-55-1.mol | [Molecular Weight]
514.66 |
| Chemical Properties | Back Directory | [Boiling point ]
674.6±55.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
4.77±0.23(Predicted) |
| Hazard Information | Back Directory | [Description]
Ganoderic acid AM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.8+/-0.7 microM. | [Uses]
Ganoderic acid AM1 (GAAM1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid AM1 shows cytotoxicity with an IC50 value of 19.8 μM for HeLa cells[1]. | [References]
[1] Yue QX, et al. Effects of triterpenes from Ganoderma lucidum on protein expression profile of HeLa cells. Phytomedicine. 2010 Jul;17(8-9):606-13. DOI:10.1016/j.phymed.2009.12.013 |
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