| Identification | Back Directory | [Name]
Ganoderic acid TR | [CAS]
862893-75-2 | [Synonyms]
Ganoderic acid TR
15alpha-hydroxy-3-oxo-5alpha-lanosta-7,9,24(E)-trien-26-oic acid
(15alpha,24E)-15-Hydroxy-3-oxolanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oic acid, 15-hydroxy-3-oxo-, (15α,24E)- | [Molecular Formula]
C30H44O4 | [MDL Number]
MFCD21333560 | [MOL File]
862893-75-2.mol | [Molecular Weight]
468.67 |
| Chemical Properties | Back Directory | [Boiling point ]
618.6±55.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
5.01±0.19(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively[1]. | [target]
5-alpha Reductase | [References]
[1] Zhu Q, et al. Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194. DOI:10.1038/srep13194 |
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