| Identification | Back Directory | [Name]
(24E)-3β-Hydroxy-5α-lanosta-7,9(11),24-trien-26-oic acid | [CAS]
86377-52-8 | [Synonyms]
Ganoderic acid Y
(24E)-3β-Hydroxy-5α-lanosta-7,9(11),24-trien-26-oic acid
(3beta,24E)-3-Hydroxylanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oicacid, 3-hydroxy-, (3b,24E)-
Lanosta-7,9(11),24-trien-26-oic acid, 3-hydroxy-, (3β,24E)- | [Molecular Formula]
C30H46O3 | [MDL Number]
MFCD21333652 | [MOL File]
86377-52-8.mol | [Molecular Weight]
454.7 |
| Chemical Properties | Back Directory | [Boiling point ]
586.3±50.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
5.01±0.19(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating[1][2]. | [Definition]
ChEBI:Ganoderic acid Y is a triterpenoid. | [target]
Antifection | [References]
[1] Chen XQ, et al. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. Phytochemistry. 2018 May;149:103-115. DOI:10.1016/j.phytochem.2018.01.007
[2] Zhang W, et al. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12. DOI:10.1016/j.bbrc.2014.05.019 |
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