| Identification | More | [Name]
4-Morpholinecarbonyl chloride | [CAS]
15159-40-7 | [Synonyms]
4-CHLOROCARBONYLMORPHOLINE
4-MORPHOLINE CARBONIC ACID CHLORIDE
4-MORPHOLINECARBONYL CHLORIDE
4-MORPHOLINYLCARBONYL CHLORIDE
MORPHOLIN-4-YLCARBONYL CHLORIDE
MORPHOLINE-4-CARBONYL CHLORIDE
MORPHOLINOCARBONYL CHLORIDE
4-Morpholinecarbonyl chloride (7CI,8CI,9CI)
4-Morpholinecarbonyl chlorid...
N-CHLOROFORMYLMORPHOLINE
Morpholincarbonylchlorid
Morpholine-4-carboxylic acid chloride | [EINECS(EC#)]
239-213-0 | [Molecular Formula]
C5H8ClNO2 | [MDL Number]
MFCD00037053 | [Molecular Weight]
149.58 | [MOL File]
15159-40-7.mol |
| Chemical Properties | Back Directory | [Boiling point ]
137-138 °C/33 mmHg (lit.) | [density ]
1.282 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.498(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Inert atmosphere,2-8°C | [form ]
clear liquid | [pka]
-2.16±0.20(Predicted) | [color ]
Colorless to Light yellow | [BRN ]
116257 | [InChI]
InChI=1S/C5H8ClNO2/c6-5(8)7-1-3-9-4-2-7/h1-4H2 | [InChIKey]
XMWFMEYDRNJSOO-UHFFFAOYSA-N | [SMILES]
C(Cl)(N1CCOCC1)=O | [CAS DataBase Reference]
15159-40-7(CAS DataBase Reference) | [EPA Substance Registry System]
15159-40-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R14:Reacts violently with water.
R36/38:Irritating to eyes and skin .
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S30:Never add water to this product .
S36:Wear suitable protective clothing .
S38:In case of insufficient ventilation, wear suitable respiratory equipment . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Uses]
Photographic intermediate | [General Description]
4-Morpholinecarbonyl chloride is a photographic intermediate. Rates of solvolysis of 4-morpholinecarbonyl chloride with N-alkyl group in aqueous binary solvents of acetone, ethanol, methanol, methanol-d, 2,2,2-trifluoroethanol, pure water and D2O has been determined. Preparation of 4-morpholinecarbonyl chloride has been reported. | [Synthesis]
4-Morpholinecarbonyl chloride is prepared by reacting morpholine hydrochloride with phosgene in an inert liquid medium such as toluene and xylene, at 50W150°C, pref. 60W120°C. The morpholine hydrochloride is prepared by dissolving 1 part by weight of morpholine in ≥4 parts of an inert liquid medium and introducing a slightly excessive HCl into the solution under agitation.
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