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15220-11-8

15220-11-8 Structure

15220-11-8 Structure
IdentificationMore
[Name]

4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT
[CAS]

15220-11-8
[Synonyms]

4-MUS
4-MU-SULFATE K
Einecs 239-272-2
4-METHYLUMBELLIFERYL SULFATE POTASSIUM
POTASSIUM 4-METHYLUMBELLIFERONE SULFATE
Potassium 4-methylumbelliferyl sulfate
4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT
4-methylumberiferryl sulfate potassium salt
4-METHYLUMBELLIFERYL SULPHATE POTASSIUM SALT
4-METHYLUMBELLIFERONE SULFATE POTASSIUM SALT
potassiuM 4-Methyl-2-oxo-2H-chroMen-7-yl sulfate
7-HYDROXY-4-METHYLCOUMARIN SULFATE POTASSIUM SALT
potassium (4-methyl-2-oxo-2H-1-benzopyran-7-yl)sulphate
4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT CRYSTALLINE
4-methyl-7-(sulfooxy)-2h-1-benzopyran-2-onpotassiumsalt
4-Methyl-7-(potassiooxysulfonyloxy)-2H-1-benzopyran-2-one
4-METHYL-7-(SULFOOXY)-2H-1-BENZOPYRAN-2-ONE POTASSIUM SALT
2H-1-Benzopyran-2-one, 4-methyl-7-(sulfooxy)-, potassium salt
4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT FOR FLUORESCENCE 99+%
2H-1-Benzopyran-2-one, 4-methyl-7-(sulfooxy)-, potassium salt (1:1)
4-MU-sulfate K *1 g* [4-MethyluMbelliferyl sulfate, potassiuM salt]
Sulfuric acid potassium 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester salt
[EINECS(EC#)]

239-272-2
[Molecular Formula]

C10H7KO6S
[MDL Number]

MFCD00016970
[Molecular Weight]

294.32
[MOL File]

15220-11-8.mol
Chemical PropertiesBack Directory
[Appearance]

Crystalline Solid
[Melting point ]

287-290°C
[storage temp. ]

2-8°C
[form ]

Powder
[color ]

White to Pale Yellow
[Water Solubility ]

Soluble in water at 5mg/ml
[Usage]

Met-enkephalin analog found in opioid extracts of brain and adrenal chromaffin cells that is an artifact generated by trichloroacetic acid extraction. MUS is used as a fluorimetric substrate for arylsulphatase enzyme. Subsitution of the hydroxyl g
[BRN ]

3803203
[Stability:]

Stable in unbuffered solution for several months at -20°
[CAS DataBase Reference]

15220-11-8(CAS DataBase Reference)
[EPA Substance Registry System]

2H-1-Benzopyran-2-one, 4-methyl-7-(sulfooxy)-, potassium salt (15220-11-8)
Safety DataBack Directory
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[F ]

8-10-21
[TSCA ]

Yes
[HS Code ]

29322090
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Sulfuric acid-->Ethyl acetoacetate-->Resorcinol-->Pyridine sulfur trioxide
Hazard InformationBack Directory
[Chemical Properties]

Crystalline Solid
[Uses]

4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.
[Uses]

Met-enkephalin analog found in opioid extracts of brain and adrenal chromaffin cells that is an artifact generated by trichloroacetic acid extraction. MUS is used as a fluorimetric substrate for arylsulphatase enzyme. Subsitution of the hydroxyl group of 4-Methylumbelliferyl sulfate potassium salt causes the excitation wavelength of the umbelliferone to shift to shorter values and also brings about a decrease in fluorescence. Fluorescence: max. Abs = 334 mm; max. Em. = 370 mm
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

15220-11-8(sigmaaldrich)
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