| Identification | More | [Name]
1-(Hydroxymethyl)cyclopropaneacetonitrile | [CAS]
152922-71-9 | [Synonyms]
[1-(HYDROXYMETHYL)CYCLOPROPYL]ACETONITRILE
2-[1-(HYDROXYMETHYL)-CYCLOPROPYL]-ACETONITRILE
Montelukast Intermediates
1-Hydroxymethyl Cyclopropyl Acetonitrile (Montelukast Intermediates)
[1-(Hydroxymethyl)cyclopropyl]acetonitrile 97%
1-(Hydroxymethyl)cyclopropaneacetonitrile
1,1-cyclopropane dimethanol cylic sufite | [EINECS(EC#)]
604-877-6 | [Molecular Formula]
C6H9NO | [MDL Number]
MFCD08235273 | [Molecular Weight]
111.14 | [MOL File]
152922-71-9.mol |
| Questions And Answer | Back Directory | [Synthesis]
Using pentaerythritol as a raw material, tribromoneopentol was obtained through bromination, followed by acetylation to give 3-bromo-2,2-bis(bromomethyl)propyl acetate. The intermediate product underwent reduction with zinc powder in a catalyst and organic solvent, followed by substitution and hydrolysis in cyanide solution and organic solvent to produce 1-(Hydroxymethyl)cyclopropaneacetonitrile. The raw materials used are simple and readily available, and the process is straightforward, suitable for large-scale industrial production.  |
| Chemical Properties | Back Directory | [Boiling point ]
245.1±13.0 °C(Predicted) | [density ]
1.098±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform, Methanol (Slightly) | [form ]
Oil | [pka]
15.10±0.10(Predicted) | [color ]
Dark Yellow to Dark Orange | [InChI]
InChI=1S/C6H9NO/c7-4-3-6(5-8)1-2-6/h8H,1-3,5H2 | [InChIKey]
WYOMLUMUVAPMKE-UHFFFAOYSA-N | [SMILES]
C1(CO)(CC#N)CC1 | [CAS DataBase Reference]
152922-71-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
1-(Hydroxymethyl)cyclopropaneacetonitrile is a reactant used in the preparation of benzothiazoles and thiazoles substituted benzyl alcohols as potent LTD4 antagonists. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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