ChemicalBook--->CAS DataBase List--->15646-46-5

15646-46-5

15646-46-5 Structure

15646-46-5 Structure
IdentificationMore
[Name]

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
[CAS]

15646-46-5
[Synonyms]

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
4-ETHOXYMETHYLENE-2-PHENYLOXAZOLIN-5-ONE
4-ETHOXYMETHYLENE-2-PHENYLOXAZOLINE-5-ONE
AKOS BBS-00001130
OXAZOLONE SENSITIZING AGENT
4-(ethoxymethylene)-2-phenyl-5(4h)-oxazolon
4-ethoxymethylene-2-phenyl-2-oxazolin-5-on
4-ETHOXYMETHYLEN-2-PHENYL-2-OXAZOLIN-5-O
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-&
4-Ethoxymethylene-2-phenyloxazolin-5-one, 98+%
Oxazolone
4-ETHOXYMETHYLENE2-PHENYLOXAZOL-5-ONE
2-Phenyl-4-(ethoxymethylene)-2-oxazoline-5-one
4-(Ethoxymethylene)-2-phenyloxazol-5(4H)-one
[EINECS(EC#)]

239-713-9
[Molecular Formula]

C12H11NO3
[MDL Number]

MFCD00003204
[Molecular Weight]

217.22
[MOL File]

15646-46-5.mol
Chemical PropertiesBack Directory
[Appearance]

white to orange or pink powder
[Melting point ]

94-96 °C (dec.)(lit.)
[Boiling point ]

357.77°C (rough estimate)
[density ]

1.2160 (rough estimate)
[refractive index ]

1.5560 (estimate)
[storage temp. ]

2-8°C
[form ]

neat
[pka]

-2.59±0.20(Predicted)
[Water Solubility ]

Soluble in methanol (50 mg/ml), and water (partly).
[BRN ]

163055
[CAS DataBase Reference]

15646-46-5(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R43:May cause sensitization by skin contact.
[Safety Statements ]

S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

RQ5786250
[HazardClass ]

IRRITANT
[HS Code ]

29349990
Hazard InformationBack Directory
[Chemical Properties]

white to orange or pink powder
[Uses]

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.
[Uses]

4-Ethoxymethylene-2-phenyloxazolin-5-one acts as sensitizing agent. It is also used as pharmaceutical intermediates.
[Definition]

ChEBI: A 1,3-oxazole compound having a phenyl substituent at the 2-position, an ethoxymethylene group at the 4-position, and an oxo group at the 5-position. It is a chemical allergen used for immunological experiments, particularly for experiments on delayed typ hypersensitivity.
Spectrum DetailBack Directory
[Spectrum Detail]

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE(15646-46-5)MS
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE(15646-46-5)1HNMR
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE(15646-46-5)IR1
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE(15646-46-5)IR2
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE(15646-46-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one, 97%(15646-46-5)
[Alfa Aesar]

4-Ethoxymethylene-2-phenyloxazolin-5-one, 98+%(15646-46-5)
[Sigma Aldrich]

15646-46-5(sigmaaldrich)
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