| Identification | Back Directory | [Name]
Dexketoprofen trometamol | [CAS]
156604-79-4 | [Synonyms]
L-Ketoprofen trometamol
dexketoprofen trometamol
D-ketoprofen troMethaMine
(s)-ketoprofen trometamol
Dexketoprofen TroMetaMol API
(S)-(+)-Form tromethamine salt
Dexketoprofen Trometamol Tablets
(S)-Ketoprofen Tromethamine Salt (Dexketoprofen Trometamol)
2-AMino-2-(hydroxyMethyl)propane-1,3-diol (S)-2-(3-benzoylphenyl)propanoate
2-amino-2-(hydroxymethyl)-1,3-propanediol (s)-3-benzoyl-alpha-methylbenzeneacetate | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C16H14O3.C4H11NO3 | [MDL Number]
MFCD00947638 | [MOL File]
156604-79-4.mol | [Molecular Weight]
375.418 |
| Chemical Properties | Back Directory | [Melting point ]
104.8-105.1° | [alpha ]
D20 -5.2° (c = 1.47 in methanol) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO, Ethanol (Slightly), Methanol (Sparingly) | [form ]
Solid | [color ]
White to Off-White | [Major Application]
pharmaceutical small molecule | [InChI]
InChI=1/C16H14O3.C4H11NO3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12;5-4(1-6,2-7)3-8/h2-11H,1H3,(H,18,19);6-8H,1-3,5H2/t11-;/s3 | [InChIKey]
QUZMDHVOUNDEKW-XAAIUDFWNA-N | [SMILES]
C(N)(CO)(CO)CO.C(C1C=CC=CC=1)(C1C=CC=C([C@H](C)C(=O)O)C=1)=O |&1:20,r| |
| Hazard Information | Back Directory | [Uses]
Dexketoprofen Trometamol is an non-steroidal anti-inflammatory drug used for the treatment of mild to moderate pain. | [Uses]
Mild to moderate pain Musculo-skeltal pain Dysmenorrhea Dental pain | [Synthesis]
In dextroketoprofen were added anhydrous ethanol, ethyl acetate and aminobutanetriol, the weight ratio of dextroketoprofen: anhydrous ethanol: ethyl acetate: aminobutanetriol = 1: 2: 7: 0.48, stirring, reflux for 30 minutes, filtered to the crystallizatio |
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