| Identification | More | [Name]
4-Chloro-2-methylphenol | [CAS]
1570-64-5 | [Synonyms]
2-METHYL-4-CHLOROPHENOL
4-CHLORO-2-CRESOL
4-CHLORO-2-METHYLPHENOL
4-CHLORO-O-CRESOL
5-CHLORO-2-HYDROXYTOLUENE
4-chloro-2-methyl-pheno
4-chloro-o-creso
ai3-24520
o-Cresol, 4-chloro-
para-chloro-ortho-cresol
p-Chloro-o-cresol
4-CHLORO-2-METHYLPHENOL, 1GM, NEAT
4-CHLORO-2-METHYLPHENOL, 1000MG, NEAT
4-Chloro-o-methylphenol
Phenol, 4-chloro-2-methyl-
4-chloro-0-cresol
4-CHLORO-ORTHO-CRESOL
4-Chlor-2-methylphenol
97-99℃
Chlorocresol (ortho-) | [EINECS(EC#)]
216-381-3 | [Molecular Formula]
C7H7ClO | [MDL Number]
MFCD00002321 | [Molecular Weight]
142.58 | [MOL File]
1570-64-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-white to slightly brownish crystalline solid | [Melting point ]
43-46 °C(lit.)
| [alpha ]
22 º (c=8,6N HCl) | [Boiling point ]
220-225 °C(lit.)
| [density ]
1.20 | [vapor pressure ]
26.66Pa at 19.85℃ | [refractive index ]
1.5449 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
0-6°C | [form ]
neat | [pka]
9.87±0.18(Predicted) | [color ]
white to brown
| [Water Solubility ]
<0.1 g/100 mL at 15 ºC | [BRN ]
1906684 | [InChIKey]
RHPUJHQBPORFGV-UHFFFAOYSA-N | [LogP]
3.09 at 20℃ | [CAS DataBase Reference]
1570-64-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Phenol, 4-chloro-2-methyl-(1570-64-5) | [EPA Substance Registry System]
1570-64-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,C,N,Xn | [Risk Statements ]
R23:Toxic by inhalation.
R35:Causes severe burns.
R50:Very Toxic to aquatic organisms.
R38:Irritating to the skin.
R21/22:Harmful in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . | [RIDADR ]
UN 3437 6.1/PG 2
| [WGK Germany ]
2
| [RTECS ]
GO7120000
| [Hazard Note ]
Toxic/Corrosive | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29081990 | [Hazardous Substances Data]
1570-64-5(Hazardous Substances Data) | [Toxicity]
mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03270, |
| Hazard Information | Back Directory | [General Description]
Dark red flakes with waxy texture. Insoluble in water. | [Reactivity Profile]
P-CHLORO-O-CRESOL(1570-64-5) can react vigorously with concentrated sodium hydroxide solutions. Also reacts with other bases, acid chlorides, acid anhydrides, and oxidizing agents. Corrodes steel, brass, copper and copper alloys [NTP, 1992)]. A large quantity left in contact with concentrated sodium hydroxide solution for 3 days reacted violently, attaining red heat and evolving fumes that ignited explosively. The heat of reaction dissipated poorly because of the high viscosity of the mixture [Quart. Safety Summ., 1957, 28, 39]. | [Air & Water Reactions]
Insoluble in water. | [Fire Hazard]
This chemical is probably combustible. | [Chemical Properties]
Off-white to slightly brownish crystalline solid | [Uses]
4-Chloro-2-methylphenol is a transformation/degredation product of herbicides found in the environment through landfills and runoff. | [Application]
4-Chloro-2-methylphenol is an important pharmaceutical intermediate ingredient used in the manufacture of herbicides (Mecoprop, MCPA, and MCPB), as an additive tracer for resist plasma etching. It is used as a closed system intermediate in the production of phenoxy herbicides. It is also used as a disinfectant or bactericide. | [Definition]
ChEBI: A member of the class of phenols that is o-cresol in which the hydrogen para to the hydroxy group is replaced by a chlorine. | [Synthesis Reference(s)]
Tetrahedron Letters, 30, p. 5215, 1989 DOI: 10.1016/S0040-4039(01)93745-1 | [Flammability and Explosibility]
Nonflammable | [Purification Methods]
Purify the phenol by crystallisation from pet ether (m 51o) and by zone melting. [Beilstein 6 H 359, 6 I 174, 6 II 332, 6 III 1264, 6 IV 1987.] |
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