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160107-07-3

160107-07-3 Structure

160107-07-3 Structure
IdentificationBack Directory
[Name]

N2-iso-Butyroyl-3'-O-methylguanosine
[CAS]

160107-07-3
[Synonyms]

N2-iso-Butyroyl-3'-O-methylguanosine
[Molecular Formula]

C15H21N5O6
[MDL Number]

MFCD31814030
[MOL File]

160107-07-3.mol
[Molecular Weight]

367.36
Chemical PropertiesBack Directory
[density ]

1.68±0.1 g/cm3(Predicted)
[pka]

9.16±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

N2-iso-Butyroyl-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
[References]

[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
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